Oral Session

Oral Session 1-12C Lymphoid Leukemia: Basic

Fri. Oct 11, 2019 3:20 PM - 4:20 PM No.12 (Tokyo International Forum, 5F G510)

Chair: Fumihiko Hayakawa (Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine)

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[OS1-12C-1] A fast and accurate diagnostic method for Ph-like ALL using the nCounter system

Kensuke Sasaki¹, Kohta Miyawaki¹, Yuichiro Semba¹, Koji Kato¹, Junpei Nogami¹, Takeshi Sugio¹, Toshihiro Miyamoto¹, Yoshikiyo Ito², Koji Nagafuji³, Takahiro Maeda¹, Koichi Akashi¹ (1.Department of Medicine and Biosystemic Science, Kyushu University, Fukuoka, Japan, 2.Department of Hematology, Imamura General Hospital, Kagoshima, Japan, 3.Division of Hematology and Oncology, Kurume University, Fukuoka, Japan)

[OS1-12C-2] The detection of T315I using ddPCR in patients with Ph+ ALL who received HSCT in the dasatinib era

Yu Akahoshi, Hideki Nakasone, Koji Kawamura, Miki Sato, Shunto Kawamura, Junko Takeshita, Nozomu Yoshino, Yukiko Misaki, Kazuki Yoshimura, Ayumi Gomyo, Aki Tanihara, Masaharu Tamaki, Machiko Kusuda, Hidenori Wada, Shunichi Kimura, Shinichi Kako, Yoshinobu Kanda (Jichi Saitama Medical Center., Saitama, Japan)

[OS1-12C-3] Simple determination of plasma ibrutinib concentration using high-performance liquid chromatography

Hiroshi Yasui¹, Takeo Yasu², Arinobu Tojo¹ (1.Hematology/Oncology, Institute of Medical Science, Tokyo Univ., Tokyo, Japan, 2.Meiji Pharmaceutical University, Tokyo, Japan)

[OS1-12C-4] STAT5B mutation and its relationship with clonal evolution in T lymphoblastic leukemia/lymphoma

Jun Kobayashi^1,2, Toru Kawakami³, Nodoka Sekiguchi^3,4, Taku Yamane², Hitoshi Sakai³, Sayaka Nishina³, Eiko Hidaka^1,5, Noriko Kubota^1,5, Takahiro Tanahashi², Yumiko Higuchi⁶, Yozo Nakazawa⁷, Hideyuki Nakazawa³, Fumihiro Ishida^2,3,6 (1.Department of Laboratory Medicine, Nagano Children's Hospital, Azumino, Japan, 2.Health and Medical Sci., Shinshu Univ., Matsumoto, Japan, 3.Hematol., Shinshu Univ., Matsumoto, Japan, 4.Comprehensive Cancer Ther., Shinshu Univ., Matsumoto, Japan, 5.Life Science Research Center, Nagano Children's Hospital, Azumino, Japan, 6.Biomedical Laboratory Sci., Shinshu Univ., Matsumoto, Japan, 7.Pediatrics, Shinshu Univ., Matsumoto, Japan)

[OS1-12C-5] Frequent STAT3 mutations in T cell receptor γδ type large granular lymphocyte

Taku Yamane¹, Toru Kawakami², Nodoka Sekiguchi³, Jun Kobayashi^1,4, Toshimitsu Ueki⁵, Hikaru Kobayashi⁵, Kaoko Sakai², Sayaka Nishina², Hitoshi Sakai², Kazuo Oshimi⁶, Yumiko Higuchi⁷, Hideyuki Nakazawa², Fumihiro Ishida^1,2,7 (1.Health and Medical Sci., Shinshu Univ., Matsumoto, Japan, 2.Hematol., Shinshu Univ., Matsumoto, Japan, 3.Comprehensive Cancer Ther., Shinshu Univ., Matsumoto, Japan, 4.Laboratory Med., Nagano Children's Hospital, Azumino, Japan, 5.Hematol., Kushiro Rosai Hosp. Kushiro, Japan, 6.Hematol., Kushiro Rosai Hosp. Kushiro, Japan, 7.Biomedical Laboratory Sci., Shinshu Univ., Matsumoto, Japan)

[OS1-12C-6] Steroids and newer agents differently regulate cytokine release by CAR-T cells and macrophages

Muneyoshi Futami¹, Keisuke Suzuki², Satomi Kato¹, Yoshio Tahara², Takayuki Mimura², Yoichi Imai¹, Yoshihiro Watanabe³, Arinobu Tojo¹ (1.Institute of Medical Science., Univ. Tokyo., Tokyo, Japan, 2.Torii Pharmaceutical., Sakura-shi, Japan, 3.Kanazawa Univ. Kanazawa, Japan)