Oral Session 1-14B Gene Diagnosis and Gene Therapy

[OS1-14B-5] A mouse model of human disease caused by gain-of-function STAT1 mutation

Moe Tamaura^1,2, Naoko Satoh², Miyuki Tsumura¹, Takaharu Sasaki², Shunsuke Kimura¹, Tomoko Kageyama², Seiichi Hayakawa¹, Takaki Asano¹, Satoshi Goda¹, Manabu Nakayama⁴, Haruhiko Koseki⁵, Osamu Ohara^6,7, Satoshi Okada¹, Hiroshi Ohno^2,3, Masao Kobayashi¹ (1.Dept. Pediatrics, Hiroshima University, Hiroshima, Japan, 2.Lab. Intestinal Ecosystem, RIKEN, Yokohama, Japan, 3.Dept. Medical Life Science, Yokohama City University, Yokohama, Japan, 4.Dept. Frontier Research and Development, Kazusa DNA Research Institute, Japan, 5.Lab. Developmental Genetics, RIKEN, Yokohama, Japan, 6.Dept. Applied Genomics, Kazusa DNA Research Institute, Kisarazu, Japan, 7.Lab. Integrative Genomics, RIKEN, Yokohama, Japan)