PRMT5 inhibition is synthetic lethal with loss of NDRG2 through the suppression of HSP90A in ATL

Tomonaga Ichikawa

Presentation information

Oral Session

Oral Session 2-10D ATL/HTLV-1: Molecular Mechanism/Therapeutic Target

Sat. Oct 12, 2019 4:00 PM - 5:00 PM No.10 (Tokyo International Forum, 4F G409)

Chair: Jun-ichirou Yasunaga (Laboratory of Virus Control, Institute for Frontier Life and Medical Sciences, Kyoto University)

[OS2-10D-5] PRMT5 inhibition is synthetic lethal with loss of NDRG2 through the suppression of HSP90A in ATL

Tomonaga Ichikawa¹, Obeid Shanab¹, Shingo Nakahata¹, Masaya Ono², Hidekatsu Iha³, Kazuhiro Morishita¹ (1.Tumor and Cellular Biochemistry, University of Miyazaki, 2.National Cancer Center Research Institute, 3.Microbiology, University of Oita)

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