Oral Session 3-14B GVHD (2)

[OS3-14B-2] MEK inhibitor trametinib enhances T cell reconstitution while suppressing xenogeneic GVHD

Hiroyuki Muranushi¹, Hidekazu Itamura², Takero Shindo^1,2, Kazutaka Kitaura³, Seiji Okada⁴, Tadasu Shini⁵, Ryuji Suzuki^3,6, Akifumi Takaori¹, Shinya Kimura² (1.Department of Hematology and Oncology, Kyoto University, Kyoto, Japan, 2.Hematology, Respiratory Medicine and Oncology, Saga University, Saga, Japan, 3.Repertoire Genesis Incorporation, Ibaraki, Japan, 4.Joint Research Center for Human Retrovirus Infection, Kumamoto, Japan, 5.BITS Co. Ltd, Tokyo, Japan, 6.Clinical Research Center, Sagamihara National Hospital, Sagamihara, Japan)