Symposium 1 Molecular Pathogenesis of Bone Marrow Failure

[SY1-5] Microenvironmental contributions to bone marrow failure and clonal evolution

Marc H.G.P. Raaijmakers (ErasmusMC Cancer Institute, department of Hematology, Rotterdam, the Netherlands)

Dr. Marc H.G.P. Raaijmakers, MD, PhD, is a professor of Hematology in the Department of Hematology at the Erasmus MC Cancer Institute, Rotterdam, the Netherlands. He completed postdoctoral research at the Department of Stem Cell and Regenerative Biology at Harvard University and the Harvard Stem Cell Institute, revealing a concept of niche-induced oncogenesis in the hematopoietic system. He (co)-authored papers and comments in leading journals including Nature, Cell, Cell Stem Cell, J. Exp. Med, Blood and Leukemia, served in the editorial boards of leading journals in the field of Hematology and provided numerous invited lectures at international meetings. He chairs the expertise center on Bone Marrow Failure and Leukemia Predisposition Syndromes at the Erasmus MC and the EHA scientific working group on Genetic Predisposition in Hematologic Cancer. His laboratory studies micro-environmental contributions to the pathogenesis of hematopoietic disease, with an emphasis on bone marrow failure and leukemogenesis. He received scholar awards from the Dutch Cancer Society, the Dutch Society of Hematology, the Dutch Ministry of Science and Innovation and the Leukemia & Lymphoma Society U.S.A. His clinical focus is in bone marrow failure syndromes, MDS and acute myeloid leukemia.