[EngO6-5] Effect of healthcare-associated infections on the length of pediatric intensive care unit stay
Introduction:
Healthcare-associated infections (HAIs) result in prolonged pediatric intensive care unit (PICU) stay and worse outcomes; however, the effect of HAIs on the length of PICU stay is unknown.
Objective:
We aimed to assess the effect of HAIs on the length of PICU stay.
Methods:
We conducted this retrospective observational study at a single tertiary children’s hospital and included all consecutive pediatric patients admitted to the PICU from 2013 to 2017. The effects of HAIs, including bloodstream infections (BSIs), pneumonia, and urinary tract infections (UTIs), on the length of PICU stay were assessed using multiple regression analysis.
Results:
In total, 2,886 patients were included, and the median age was 16 (interquartile range, 4–59) months. There were 67 BSI cases, 43 pneumonia cases, and 57 UTI cases. After adjusting for age in months, sex, pediatric index of mortality 2, postoperative admission, elective admission, use of extracorporeal membrane oxygenation, vasoactive inotrope, mechanical ventilation, renal replacement therapy, use of steroids, use of antibiotics, diagnostic category, mortality in PICU, we observed that BSI, pneumonia, and UTI were associated with 18.5 days (95% confidence interval [CI], 16.3–20.6), 27.6 days (24.8–30.3), and 13.2 days (10.8–15.5) of prolonged PICU stay.
Conclusion:
HAIs considerably affected the length of PICU stay; therefore, preventing HAIs is important for patients’ prognosis and medical economics.
![image/EngO6-5.jpg](https://confit-sfs.atlas.jp/customer/jsicm2019/image/EngO6-5.jpg)
Healthcare-associated infections (HAIs) result in prolonged pediatric intensive care unit (PICU) stay and worse outcomes; however, the effect of HAIs on the length of PICU stay is unknown.
Objective:
We aimed to assess the effect of HAIs on the length of PICU stay.
Methods:
We conducted this retrospective observational study at a single tertiary children’s hospital and included all consecutive pediatric patients admitted to the PICU from 2013 to 2017. The effects of HAIs, including bloodstream infections (BSIs), pneumonia, and urinary tract infections (UTIs), on the length of PICU stay were assessed using multiple regression analysis.
Results:
In total, 2,886 patients were included, and the median age was 16 (interquartile range, 4–59) months. There were 67 BSI cases, 43 pneumonia cases, and 57 UTI cases. After adjusting for age in months, sex, pediatric index of mortality 2, postoperative admission, elective admission, use of extracorporeal membrane oxygenation, vasoactive inotrope, mechanical ventilation, renal replacement therapy, use of steroids, use of antibiotics, diagnostic category, mortality in PICU, we observed that BSI, pneumonia, and UTI were associated with 18.5 days (95% confidence interval [CI], 16.3–20.6), 27.6 days (24.8–30.3), and 13.2 days (10.8–15.5) of prolonged PICU stay.
Conclusion:
HAIs considerably affected the length of PICU stay; therefore, preventing HAIs is important for patients’ prognosis and medical economics.
![image/EngO6-5.jpg](https://confit-sfs.atlas.jp/customer/jsicm2019/image/EngO6-5.jpg)