第46回日本集中治療医学会学術集会

Presentation information

English Session

[EngO7] English Session7

Sat. Mar 2, 2019 3:05 PM - 4:05 PM 第11会場 (国立京都国際会館1F Room C-2)

Chair:Kenji Wakabayashi(Department of Intensive Care Medicine, Tokyo Medical and Dental University, Japan)

[EngO7-2] Potential benefits of acute-phase cardiac rehabilitation in the intensive care unit for patients with cardiovascular disease -A retrospective observational study-

Nobuaki Hamazaki1, Ryota Matsuzawa1, Kohei Nozaki1, Takafumi Ichikawa1, Kentaro Kamiya2, Kazumasa Miida1, Tomotaka Koike3, Emi Maekawa4, Masayasu Arai5, Takashi Masuda2 (1.Department of Rehabilitation, Kitasato University Hospital, Japan, 2.Department of Rehabilitation, Kitasato University School of Allied Health Sciences, Japan, 3.Intensive Care Center, Kitasato University Hospital, Japan, 4.Department of Cardiovascular Medicine, Kitasato University School of Medicine, Japan, 5.Department of Anesthesiology, Kitasato University School of Medicine, Japan)

Background: Early rehabilitation in intensive care unit (ICU), including the early mobility therapy, has been documented to improve the clinical outcomes in critically ill patients. However, the effectiveness of acute-phase cardiac rehabilitation (CR) during ICU treatment have not been thoroughly evaluated in patients with cardiovascular disease (CVD). The aim of this study was to investigate the potential benefits of acute-phase CR in the ICU on clinical outcomes in CVD patients.
Methods: We studied 2034 CVD patients who admitted ICU of a university hospital and received CR from 2009 to 2017. Disease etiology, comorbid conditions, ICU treatment, length of ICU stay and hospital stay, duration from admission to walking independence, and six-minute walk distance at hospital discharge were retrospectively obtained from electronic database. Patients were classified into 2 groups based on the presence or absence of cardiac rehabilitation during ICU treatment (ICU-CR group: n=1057, Control group: n=977). We compared the clinical outcomes between the 2 groups using Kaplan-Meier method and analysis of covariance with adjustment for cofounding factors.
Results: As compared with the Control group, the ICU-CR group showed significantly shorter length of ICU stay (estimated mean difference [EMD]: -1.568, P = 0.001) and length of hospital stay (EMD: -3.608, P <0.001) even after adjustment for confounding factors. The duration from admission to walking independence was significantly earlier in the ICU-CR group than in that of the Control (Figure). There were no significant differences in 6-minute walk distance between the 2 groups.
Conclusion: The acute-phase CR in the ICU was considered beneficial to improve clinical outcomes in CVD patients.
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