Mini-Oral Session

[MO16] Mini-Oral Session 16　Translational Research / Clinical Pharmacology 2（Immunotherapy）
【E】

Thu. Feb 17, 2022 2:10 PM - 3:10 PM Room 10 (Royal Room, 1F, The Prince Kyoto Takaragaike)

Chair：Kazuo Kasahara（Department of Respiratory Medicine, Kanazawa University），Shigehisa Kitano（The Cancer Institute Hospital of JFCR）

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[MO16-1] Development of adaptive immunotherapy using neoantigen (NeoAg)-specific T cell receptor (TCR)-gene transduced T cells

^○Hidetoshi Sumimoto¹, Koji Terada², Agata Yasutoshi², Yataro Daigo^1,3 (1.Department of Medical Oncology, Shiga University of Medical Science, 2.Department of Biochemistry and Molecular Biology, Shiga University of Medical Science, 3.Center for Antibody and Vaccine Therapy, Research Hospital, Institute of Medical Science, The University of Tokyo)

[MO16-2] Clinical impact of serum IgG fractions in advanced non-small cell lung cancer treated with immune checkpoint inhibitors

^○Jun Oyanagi^1,2, Yasuhiro Koh^1,2, Yasuyuki Akiyama³, Atsushi Morimoto³, Koichi Sato¹, Shunsuke Teraoka¹, Daichi Fujimoto¹, Nahomi Tokudome¹, Atsushi Hayata¹, Yuichi Ozawa¹, Hiroaki Akamatsu¹, Masanori Nakanishi¹, Hiroki Ueda¹, Nobuyuki Yamamoto^1,2 (1.Internal Medicine III, Wakayama Medical University, 2.Center for Biomedical Sciences, CIMS, Wakayama Medical University, 3.Tosoh Corporation)

[MO16-3] Tumor expression of cGAS impacts on PD1/L1 inhibitors efficacy in PD-L1-high NSCLC

^○Yuichi Ozawa¹, Yuhei Harutani¹, Jun Oyanagi^1,2, Akamatsu Hiroaki¹, Murakami Eriko¹, Sato Kouichi¹, Ryota Shibaki¹, Takeya Sugimoto¹, Atsushi Hayata¹, Shunsuke Teraoka¹, Tokudome Nahomi¹, Hiroki Ueda^1,3, Masanori Nakanishi¹, Yasuhiro Koh^1,2, Nobuyuki Yamamoto^1,2 (1.Department of Pulmonary Medicine and Medical Oncology, Wakayama Medical University, 2.Center for Biomedical Sciences, Wakayama Medical University, 3.Oncology Center, Wakayama Medical University)

[MO16-4] Intestinal microbiota and gene expression reveal similarity and dissimilarity between irAE colitis and UC

^○Kazuko Sakai¹, Marco Develasco¹, Tomoyuki Nagai², Kazuomi Ueshima², Takaaki Chikugo³, Yurie Kura¹, Takayuki Takahama⁴, Hidetoshi Hayashi⁴, Kazuhiko Nakagawa⁴, Masatoshi Kudo², Kazuto Nishio¹ (1.Department of Genome Biology, Kindai University Faculty of Medicine, 2.Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, 3.Department of Diagnostic Pathology, Kindai University Faculty of Medicine, 4.Department of Medical Oncology, Kindai University Faculty of Medicine)

[MO16-5] Gender survival disparities in the era of immune checkpoint inhibitors (ICI)

^○Mohammed Hussein Safi¹, Aman Wang¹, Abdullah Shopit², Dario Trapani³, Xiu Shan¹, Jiwei Liu¹ (1.Department of Oncology, First Affiliated Hospital of Dalian Medical University, 2.Medicine & Collage of Pharmacy, Department of Pharmacology, Dalian Medical University, Dalian, China, 3.IEO - Istituto Europeo di Oncologia)

[MO16-6] S-531011, a novel anti-human CCR8 antibody: Antibody screening and evaluation of biological profiles

^○Yoshikawa Mai¹, Nagira Yoji¹, Nagira Morio¹, Yoshida Tetsuya¹, Yoshida Shinpei¹, Soh Tetsuyoshi¹, Wada Hisashi^2,3, Ohkura Naganari^4,5, Takahashi Tatsuya¹ (1.SHIONOGI & CO., LTD., Japan, 2.Department of Clinical Research in Tumor Immunology, Graduate School of Medicine, Osaka University, 3.Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, 4.Department of Frontier Research in Tumor Immunology, Graduate School of Medicine, Osaka University, 5.Experimental Immunology, Immunology Frontier Research Center, Osaka University)

[MO16-7] S-531011, a novel anti-human CCR8 antibody: antitumor effects through depleting tumor-infiltrating CCR8-positive Tregs

^○Ryohei Nagai¹, Morio Nagira¹, Wataru Nogami¹, Michinari Hirata¹, Azumi Ueyama¹, Mai Yoshikawa¹, Naganari Ohkura^2,3, Hisashi Wada^4,5, Yoji Nagira¹ (1.SHIONOGI & CO., LTD., 2.Department of Frontier Research in Tumor Immunology, Graduate School of Medicine, Osaka University, 3.Experimental Immunology, Immunology Frontier Research Center, Osaka University, 4.Department of Clinical Research in Tumor Immunology, Graduate School of Medicine, Osaka University, 5.Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University)