Designated presentation

[SY4] Symposium: Pathophysiology of tau protein

Thu. Sep 10, 2020 4:10 PM - 5:40 PM A (Zoom A)

Chair person:Naruhiko Sahara(National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology), Sumihiro Maeda

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Chair's remarks (4:10 PM - 4:12 PM)

4:12 PM - 4:32 PM

[SY4-01] Considering the abnormality of pathological tau; lessons from physiological tau!

*Tomohiro Miyasaka¹, Ayaka Hagita¹, Hiroaki Misono² (1. Neuropathology, Faculty of Life and Medical Sciences, Doshisha University, 2. Laboratory of Ion Channel Pathophysiology, Graduate School of Brain Science, Doshisha University)

4:32 PM - 4:52 PM

[SY4-02] Nasal vaccine for the treatment of tauopathy

*Keiko Imamura^1,2,3, Hiroki Takeuchi¹, Naruhiko Sahara⁴, Makoto Inoue⁵, Takeshi Tabira⁶, Makoto Higuchi³, Haruhisa Inoue^1,2,3,7 (1. Center for iPS Cell Research and Application (CiRA), Kyoto University, 2. iPSC-based Drug Discovery and Development Team, RIKEN BioResource Research Center (BRC) , 3. Medical-risk Avoidance based on iPS Cells Team, RIKEN Center for Advanced Intelligence Project (AIP), 4. Department of Functional Brain Imaging, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 5. Sumitomo Dainippon Pharma Co., Ltd., 6. Department of Diagnosis, Prevention and Treatment of Dementia, Faculty of Medicine, Juntendo University, 7. Institute for Advancement of Clinical and Translational Science, Kyoto University)

4:52 PM - 5:12 PM

[SY4-03] Towards elucidation of propagation mechanism of tau pathology in Alzheimer's disease

*Hiroki Sasaguri^1,2 (1. RIKEN Center for Brain Science, 2. Department of Neurology and Neurological Science, Tokyo Medical and Dental University)

5:12 PM - 5:32 PM

[SY4-04] Selective disruption of inhibitory synapses leading to neuronal hyperexcitability at an early stage of tau pathogenesis in a mouse model

*Masafumi Shimojo¹ (1. National Institutes for Quantum and Radiological Science and Technology)

Discussion (5:32 PM - 5:40 PM)

Session information