[I-P-065] 心血管MRIにて計測した体右心室容量と機能は、三尖弁閉鎖不全の程度と関連するか？
Keywords:systemic right ventricle, tricuspid valve regurgitation, cardiovascular MRI
Background: In patients with congenital corrected transposition of the great arteries (ccTGA) and complete transposition of the great arteries following an atrial switch operation (dTGA), the main concern has been the long-term performance of the morphologic right ventricle (RV) in association with tricuspid valve regurgitation (TR) when it remains as systemic RV.
Objective: To assess the relationship between the degree of TR and systemic right ventricular dysfunction by cardiovascular MRI (CMR).
Methods: We retrospectively examined patients with ccTGA and dTGA. We measured right ventricular end-diastolic volume (RVEDV), end-systolic volume (RVESV), stroke volume (RVSV) and ejection fraction (RVEF) using conventional short-axis cine MR imaging, and tricuspid regurgitant fraction (TRF) using phase-contrast MR imaging.
Results: We identified 10 patients (7 ccTGA and 3 dTGA) and the mean age was 27+/-18 years. Three patients had mild TR (10%<TRF<20%), 5 had moderate TR (20%<TRF<40%) and 2 had severe TR (40%<TRF). The measured RVEDV (134 ml/m2 vs. 148 ml/m2 vs. 153 ml/m2, p=0.45), RVESV (71 ml/m2 vs. 87 ml/m2 vs. 90 ml/m2, p=0.42), RVSV (63 ml/m2 vs. 61 ml/m2 vs. 63 ml/m2, p=0.38) and RVEF (45% vs. 41% vs. 42%, p=0.58) were not significantly different for patients with mild, moderate and severe TR, respectively.
Conclusion: The degree of TR was not associated with increased right ventricular volume or decreased right ventricular function by CMR in ccTGA and dTGA. The degree of TR alone may not fully explain the heterogeneity in systemic right ventricular size and function.
Objective: To assess the relationship between the degree of TR and systemic right ventricular dysfunction by cardiovascular MRI (CMR).
Methods: We retrospectively examined patients with ccTGA and dTGA. We measured right ventricular end-diastolic volume (RVEDV), end-systolic volume (RVESV), stroke volume (RVSV) and ejection fraction (RVEF) using conventional short-axis cine MR imaging, and tricuspid regurgitant fraction (TRF) using phase-contrast MR imaging.
Results: We identified 10 patients (7 ccTGA and 3 dTGA) and the mean age was 27+/-18 years. Three patients had mild TR (10%<TRF<20%), 5 had moderate TR (20%<TRF<40%) and 2 had severe TR (40%<TRF). The measured RVEDV (134 ml/m2 vs. 148 ml/m2 vs. 153 ml/m2, p=0.45), RVESV (71 ml/m2 vs. 87 ml/m2 vs. 90 ml/m2, p=0.42), RVSV (63 ml/m2 vs. 61 ml/m2 vs. 63 ml/m2, p=0.38) and RVEF (45% vs. 41% vs. 42%, p=0.58) were not significantly different for patients with mild, moderate and severe TR, respectively.
Conclusion: The degree of TR was not associated with increased right ventricular volume or decreased right ventricular function by CMR in ccTGA and dTGA. The degree of TR alone may not fully explain the heterogeneity in systemic right ventricular size and function.