[II-OR28-01] Ｆeature tracking MR strainによる術後ファロー四徴症の右室心筋deformationと三尖弁変位の評価
Keywords:repaired tetralogy of Fallot, RV myocardial deformation, TV displacement
Objective: To investigate into correlation between right ventricular (RV) myocardial deformation and tricuspid valve (TV) displacement in repaired tetralogy of Fallot (TOF) using new MR tracking program.
Methods: In 50 repaired TOF patients (26.4+/-8.1 years) and 15 normal controls (30.1+/-15.2 years), developing cardiovascular MR software performed average longitudinal and circumferential strain, strain rate (LS, LSR and CS, CSR) in mid-systole (MS) and end-diastole (ED). As well, anterior and septal TV displacement relative to the apex were measured at end-systole (ES) as the shortest distance. The displacement velocities at basal lateral and septal segment in MS and early ED were calculated.
Results: LS was reduced in repaired TOF compared to controls while CS was preserved. LS and CS decreased with increasing RV end-diastolic (EDV) and -systolic (ESV) volume (LS & ESV r=0.32; CS & EDV r=0.41; CS & ESV r=0.52) and decreasing RV ejection fraction (EF) (LS & EF r=-0.55; CS & EF r=-0.52). Increased anterior and septal TV displacement in ES as decreased shortening correlated positively RV volume (r=0.66 and 0.63), negatively RVEF (r=-0.44 and -0.36) and LS (r=0.34 and 0.31). Decreased basal lateral displacement velocities in MS and ED as greater shortening were associated with improved LS, LSR in MS (r=-0.57 and -0.48) and LSR in ED (r=-0.45).
Conclusions: The correlations associated LS and CS with RV volume and function suggest that preservation of CS is important in maintaining RV function. Greater lateral displacement velocity is associated with improved RV contractility.
Methods: In 50 repaired TOF patients (26.4+/-8.1 years) and 15 normal controls (30.1+/-15.2 years), developing cardiovascular MR software performed average longitudinal and circumferential strain, strain rate (LS, LSR and CS, CSR) in mid-systole (MS) and end-diastole (ED). As well, anterior and septal TV displacement relative to the apex were measured at end-systole (ES) as the shortest distance. The displacement velocities at basal lateral and septal segment in MS and early ED were calculated.
Results: LS was reduced in repaired TOF compared to controls while CS was preserved. LS and CS decreased with increasing RV end-diastolic (EDV) and -systolic (ESV) volume (LS & ESV r=0.32; CS & EDV r=0.41; CS & ESV r=0.52) and decreasing RV ejection fraction (EF) (LS & EF r=-0.55; CS & EF r=-0.52). Increased anterior and septal TV displacement in ES as decreased shortening correlated positively RV volume (r=0.66 and 0.63), negatively RVEF (r=-0.44 and -0.36) and LS (r=0.34 and 0.31). Decreased basal lateral displacement velocities in MS and ED as greater shortening were associated with improved LS, LSR in MS (r=-0.57 and -0.48) and LSR in ED (r=-0.45).
Conclusions: The correlations associated LS and CS with RV volume and function suggest that preservation of CS is important in maintaining RV function. Greater lateral displacement velocity is associated with improved RV contractility.