[_OS4] 一般口演4
ALL 2

Oral Session 4　 ALL 2

Wed. Nov 14, 2018 2:40 PM - 3:40 PM 第4会場 (みやこめっせ B1F 大会議室)

座長:今村俊彦（京都府立医科大学小児科）, 今井千速（新潟大学医療学系小児科学分野）

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[OS4-1-1] 急性リンパ性白血病に対するbarasertibの効果に関する基礎的検討
In Vitro Drug Testing of Barasertib in Childhood Acute Lymphoblastic Leukemia

Hiroaki Goto, Yuki Yoshino, Wataru Nakamura, Sachio Fujita, Naoyuki Miyagawa, Akiko Hayashi, Tomoko Yokosuka, Satoshi Hamanoue, Fuminori Iwasaki, Masae Shiomi, Shoko Goto (Division of Hematology/Oncology, Kanagawa Children’s Medical Center, Yokohama, Japan)

[OS4-1-2] 高二倍体小児ALLにおける4, 10, 17番染色体のtriple trisomyとASNS遺伝子メチル化の関連性
Association between asparaginase synthetase gene methylation and triple trisomy of chromosomes 4, 10, and 17 in high-hyperdiploid childhood ALL

Atsushi Watanabe¹, Tamao Shinohara¹, Shinpei Somazu¹, Hiroko Saito¹, Hiroko Oshiro¹, Hiroki Sato¹, Kazuya Takahashi¹, Kumiko Goi¹, Masako Abe¹, Keiko Kagami¹, Kunio Miyake², Takeshi Inukai¹ (1.Department of Pediatrics, University of Yamanashi, Yamanashi, Japan, 2.Department of Health Sciences, University of Yamanashi, Yamanashi, Japan)

[OS4-1-3] T-ALL細胞株におけるL-asparaginase感受性とASNS遺伝子メチル化状態との関連性
Association of L-asparaginase sensitivity with asparaginase synthetase (ASNS) gene methylation status in T-ALL cell lines

Koshi Akahane¹, Atsushi Watanabe¹, Kunio Miyake², Tamao Shinohara¹, Daisuke Harama¹, Yasushi Murakami¹, Kumiko Goi¹, Kanji Sugita¹, Takeshi Inukai¹ (1.Department of Pediatrics, Faculty of Medicine, University of Yamanashi, Chuo, Japan, 2.Department of Health Sciences, Graduate School of Interdisciplinary Research, University of Yamanashi, Chuo, Japan)

[OS4-1-4] B前駆細胞急性リンパ性白血病のステロイド感受性におけるゲノムワイド関連解析
Association of inherited genetic variants with glucocorticoid sensitivity in B-cell precursor acute lymphoblastic leukemia

Tamao Shinohara¹, Atsushi Watanabe¹, Keiko Kagami¹, Masako Abe¹, Koshi Akahane¹, Kumiko Goi¹, Kanji Sugita¹, Kevin Urayama², Yukinori Okada³, Takeshi Inukai¹ (1.Department of Pediatrics, University of Yamanashi, Yamanashi, Japan, 2.Department of Social Medicine, National Center for Child Health and Development, Tokyo, Japan, 3.Osaka University, Graduate School of Medicine, Department of statistical genetics, Osaka, Japan)

[OS4-1-5] 急性リンパ性白血病細胞株において3つの遺伝子がエピジェネティック修飾薬のターゲットである
Detection of Three Candidate Target Genes of Epigenetic Modifiers in Acute Lymphoblastic Leukemia Cell Lines

Kimiyoshi Sakaguchi (Department of Pediatrics, Hamamatsu University School of Medicine, Hamamatsu, Japan)

[OS4-1-6] 患者の年齢と肥満度の6-メルカプトプリン感受性への影響
Effect of patient’s age and degree of obesity on 6-MP tolerability in acute lymphoblastic leukemia

Yoichi Tanaka¹, Katsuyoshi Koh², Atsushi Manabe³ (1.Department of Clinical Pharmacy, Center for Clinical Pharmacy and Sciences, School of Pharmacy, Kitasato University, Tokyo, Japan, 2.Department of Hematology/Oncology, Saitama Children’s Medical Center, Saitama, Japan, 3.Department of Pediatrics, St. Luke’s International Hospital, Tokyo, Japan)

Session information

[_OS4] 一般口演4 ALL 2

Oral Session 4 ALL 2

[OS4-1-1] 急性リンパ性白血病に対するbarasertibの効果に関する基礎的検討In Vitro Drug Testing of Barasertib in Childhood Acute Lymphoblastic Leukemia

[OS4-1-2] 高二倍体小児ALLにおける4, 10, 17番染色体のtriple trisomyとASNS遺伝子メチル化の関連性Association between asparaginase synthetase gene methylation and triple trisomy of chromosomes 4, 10, and 17 in high-hyperdiploid childhood ALL

[OS4-1-3] T-ALL細胞株におけるL-asparaginase感受性とASNS遺伝子メチル化状態との関連性Association of L-asparaginase sensitivity with asparaginase synthetase (ASNS) gene methylation status in T-ALL cell lines

[OS4-1-4] B前駆細胞急性リンパ性白血病のステロイド感受性におけるゲノムワイド関連解析Association of inherited genetic variants with glucocorticoid sensitivity in B-cell precursor acute lymphoblastic leukemia

[OS4-1-5] 急性リンパ性白血病細胞株において3つの遺伝子がエピジェネティック修飾薬のターゲットであるDetection of Three Candidate Target Genes of Epigenetic Modifiers in Acute Lymphoblastic Leukemia Cell Lines

[OS4-1-6] 患者の年齢と肥満度の6-メルカプトプリン感受性への影響Effect of patient’s age and degree of obesity on 6-MP tolerability in acute lymphoblastic leukemia