[_ES4] 英語口演4
血液基礎

[ES4-2-2] 小児T細胞性急性リンパ性白血病のDNAメチル化による分類と変異・発現・分化段階・予後との強い関連性
DNA methylation-based characterization of T-cell acute lymphoblastic leukemia well correlated with genetic features, prognosis and differentiation stages

Shunsuke Kimura^1,2, Masafumi Seki¹, Tomoko Kawai³, Kenichi Yoshida⁴, Tomoya Isobe¹, Hiroo Ueno⁴, Yusuke Shiozawa⁴, Hiromichi Suzuki⁴, Yuichi Shiraishi⁵, Kentaro Ohki⁶, Motohiro Kato⁶, Katsuyoshi Koh⁷, Ryoji Kobayashi⁸, Takao Deguchi⁹, Yoshiko Hashii¹⁰, Toshihiko Imamura¹¹, Atsushi Sato¹², Nobutaka Kiyokawa⁶, Atsushi Manabe¹³, Masashi Sanada¹⁴, Akira Ohara¹⁵, Keizo Horibe¹⁴, Masao Kobayashi², Akira Oka¹, Yasuhide Hayashi¹⁶, Satoru Miyano⁵, Kenichiro Hata³, Seishi Ogawa⁴, Junko Takita¹ (1.Department of Pediatrics, The University of Tokyo, Tokyo, Japan, 2.Department of Pediatrics, Hiroshima University, Hiroshima, Japan, 3.Department of Maternal-Fetal Biology, National Research Institute for Child Health and Development, Japan, 4.Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 5.Human Genome Center Institute of Medical Science, The University of Tokyo, Japan, 6.Department of Pediatric Hematology and Oncology Research, National Research Institute for Child Health and Development, Tokyo, Japan, 7.Department of Hematology/Oncology, Saitama Children’s Medical Center, Saitama, Japan, 8.Department of Pediatrics, Sapporo Hokuyu Hospital, Sapporo, Japan, 9.Children’s Cancer Center, National Center for Child Health and Development, Tokyo, Japan, 10.Department of Pediatrics, Osaka University Graduate School of Medicine, Suita, Japan, 11.Department of Pediatrics, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan, 12.Department of Hematology and Oncology, Miyagi Children’s Hospital, Sendai, Japan, 13.Department of Pediatrics, St. Luke’s International Hospital, Tokyo, Japan, 14.Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Japan, 15.Department of Pediatrics, Toho University, Tokyo, Japan, 16.Gunma Children’s Medical Center, Maebashi, Japan)