^○Saori Koh ¹, Mikiko Nakamura ², Akihiro Hisaka ³, Hiroshi Suzuki ⁴ (1.Laboratory for Safety Assessment and ADME, Asahi Kasei Pharma Corporation, 2.Translational Clinical Research Science & Strategy Dept., Chugai Pharmaceutical Co, Ltd, 3.Clinical Pharmacology and Pharmacometrics, Graduate School of Pharmaceutical Sciences, Chiba University, 4.Department of Pharmacy, The University of Tokyo Hospital, The University of Tokyo)

^○Yumiko Akamine ¹, Masatomo Miura ¹, Hisakazu Komori ², Hiroyuki Kusuhara ³, Ikumi Tamai ², Ichiro Ieiri ⁴, Norio Yasui-Furukori ⁵, Tsukasa Uno ⁶ (1.Department of Pharmacy, Akita University Hospital, 2.Faculty of Pharmaceutical Science, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 3.Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 4.Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, 5.Department of Neuropsychiatry, Hirosaki University School of Medicine)

^○Sumio Ohtsuki ^1,2,3, Takuya Kuno ^2,3, Mio Hirayama ^1,2,3, Shingo Ito ^1,2,3 (1.Faculty of Life Sciences, Kumamoto University, 2.Graduate School of Pharmaceutical Sciences, Kumamoto University, 3.CREST, AMED)

^○Kosuke Yokobori , Kaoru Kobayashi , Ikuko Azuma , Kan Chiba (Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University)

^○Yoshiyuki Kubo , Akiko Obata , Shin-ichi Akanuma , Ken-ichi Hosoya (Department of Pharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama)

^○Takahiro Yamashiro ¹, Tomoya Yasujima ¹, Kinya Ohta ¹, Katsuhisa Inoue ², Yayoi Hayashi ³, Hiroaki Yuasa ¹ (1.Graduate School of Pharmaceutical Sciences, Nagoya City University, 2.School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 3.School of Pharmacy, Kinjo Gakuin University)

^○Azusa Futatsugi , Yusuke Masuo , Noritaka Nakamichi , Yukio Kato (Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University)

^○Carsten Ehrhardt , Sabrina Nickel , Mohammed Ali Selo , Caoimhe G. Clerkin , Matthias Meinhardt (School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute, Trinity College Dublin)

^○Ryo Ito , Tomomi Furihata , Shota Suzuki , Zhou Xujia , Kan Chiba (Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University)

^○Junji Furukawa ¹, Katsuhisa Inoue ², Kinya Ohta ¹, Tomoya Yasujima ¹, Hiroaki Yuasa ¹ (1.Graduate School of Pharmaceutical Sciences, Nagoya city University, 2.School of Pharmacy, Tokyo University of Pharmacy and Life Sciences)

^○Yutaro Sekiguchi ¹, Kinya Ohta ¹, Tomoya Yasajima ¹, Katsuhisa Inoue ², Hiroaki Yuasa ¹ (1.Graduate School of Pharmaceutical Sciences, Nagoya City University, 2.School of Pharmacy, Tokyo University of Pharmacy and Life Sciences)

^○Takeshi Sakata ¹, Remi Magnan ¹, Yann Courbebaisse ², John Keogh ³ (1.SOLVO Biotechnology, 2.Bertin Pharma, 3.JPK Consulting)

^○Christian Lechner ¹, Naoki Ishiguro ¹, Ayano Fukuhara ¹, Hidetada Shimizu ¹, Naoko Ohtsu ¹, Masahito Takatani ¹, Hiroyuki Kusuhara ² (1.Pharmacokinetics and Non-Clinical Safety Department, Nippon Boehringer Ingelheim Co., Ltd., 2.Laboratory of Molecular Pharmaceutics, Graduate School of Pharmaceutical Sciences, The University of Tokyo)

^○Atsushi Kawase , Seiji Hata , Mai Takagi , Masahiro Iwaki (Department of Pharmacy, Faculty of Pharmacy, Kinki University)

^○Hiroki Yamakawa ¹, Tomoko Watanabe ¹, Yukari Kamikozawa ¹, Toshiyuki Kume ¹, Rikiya Ohashi ² (1.DMPK Research Laboratories, Research Core Unit, Research Division, Mitsubishi Tanabe Pharma Corporation, 2.Biology Research Laboratories, Research Core Unit, Research Division, Mitsubishi Tanabe Pharma Corporation)

^○Saki Izumi , Yoshitane Nozaki , Takafumi Komori (Eisai Co. Ltd.)

^○Takeshi Miyake , Hiroyuki Kusuhara (The laboratory of molecular pharmacokinetics, The department of pharmaceutical science, University of Tokyo)

^○Yu Sato , Takamitsu Sasaki , Yu Arai , Takashi Kumagai , Kiyoshi Nagata (Department of Environmental and Health Sciences, Tohoku Pharmaceutical University)

^○Mika Nagai ^1,2, Yoshihiro Konno ¹, Shinji Yamashita ³, Kouichi Yoshinari ² (1.Pharmacokinetics and Safety Department, Drug Research Center, Kaken Pharmaceutical Co., Ltd., 2.Department of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka, 3.Faculty of Pharmaceutical Sciences, Setsunan University)

^○Mariko Iwase ¹, Ken-ichi Fujita ², Yuki Nishimura ¹, Katsuji Oguchi ¹ (1.Department of pharmacology, School of medicine, Showa University, 2.Institute of Molecular Oncology, Showa University)

^○Akira Okada ¹, Miyu Hirano ¹, Hikaru Koyama ², Keizo Fukushima ¹, Nobuyuki Sugioka ¹ (1.Department of Clinical Pharmacokinetics, Faculty of Pharmaceutical Sciences, Kobe Gakuin University, 2.Department of Hospital Pharmacy, Kyoto Prefectural University of Medicine)

^○Shunya Sasaki ¹, Jonathan Danaceau ², Erin Chambers ² (1.Nihon Waters K.K., 2.Waters Corporation)

^○Toshiro Niwa ¹, Norie Murayama ², Yurie Imagawa ¹, Hiroshi Yamazaki ² (1.School of Pharmacy, Shujitsu University, 2.Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University)

^○Yoshiyuki Igawa ^1,2, You Nishizawa ¹, Kayoko Ohura ¹, Yasuhiro Uno ³, Masakiyo Hosokawa ⁴, Teruko Imai ¹ (1.Kumamoto University, 2.Daiichisankyo Co., Ltd., 3.Shin Nippon Biomedical Laboratories, Ltd., 4.Chiba Institute of Science)

^○Kaori Yasuda ¹, Yuasa Iwanaga ¹, Kazuaki Ogawa ¹, Hiroki Mano ¹, Miho Ohta ², Masaki Kamakura ¹, Shinichi Ikushiro ¹, Toshiyuki Sakaki ¹ (1.Department of Biotechnology, Toyama Prefectural University, 2.Development Nourishment Department, Soai University)

^○Eri Tohyama ¹, Kaori Yasuda ¹, Kazuaki Ogawa ¹, Masashi Takano ², Atsushi Kittaka ², Masaki Kamakura ¹, Shinichi Ikushiro ¹, Toshiyuki Sakaki ¹ (1.Department of Biotechnology, Toyama Prefectural University, 2.Faculty of Pharmaceutical Sciences, Teikyo University)

^○Yuuka Masuyama ¹, Miyu Nishikawa ^1,2, Kaori Yasuda ¹, Toshiyuki Sakaki ^1,2, Shinichi Ikushiro ¹ (1.Department of Biotechnology, Faculty of Engineering, Toyama Prefectural University, 2.IMIZU RESEARCH CENTER, TOPUBIO RESEARCH., Co. Ltd.)

^○Kazumi Sugihara ¹, Akiho Okazaki ¹, Yuka Akimoto ¹, Yoshitaka Tayama ¹, Shigeyuki Kitamura ², Shigeru Ohta ³ (1.Faculty of Pharmaceutical Sciences, Hiroshima International University,, 2.Nihon Pharmaceutical University, 3.Graduate School of Biomedical & Health Sciences, Hiroshima University)

^○Masato Takahashi , Kenta Mizoi , Kei Sakamoto , Masami Haba , Masakiyo Hosokawa (Chiba Institute of Science)

^○Tohru Mizutare ^1,2, Takushi Kanazu ¹, Yoshitaka Yamaguchi ¹, Seigo Sanoh ², Sigeru Ohta ² (1.Drug Metabolism & Pharmacokinetics, Research Laboratory for Development, Shionogi & Co., Ltd., 2.Graduate School of Biomedical & Health Sciences, Hiroshima University)

^○Koichi Takahashi ^1,2, Kunihiro Yoshisue ¹, Masato Chiba ¹, Takeo Nakanishi ², Ikumi Tamai ² (1.Pharmacokinetics Research Laboratories, Discovery and Preclinical Research Division, Taiho Pharmaceutical Company, Ltd., 2.Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University)

^○Béatrice Lopez ¹, Fabrice Guillet ¹, Yasuhiko Ohkaru ², Françoise Brée ¹, Pierre-Jaques Ferret ³ (1.EUROSAFE, 2.KAC Co., Ltd., 3.PIERRE FABRE DERMO COSMETIQUE)

^○Naoya Matsumura ¹, Misato Nakanishi ², Yoshinobu Hamada ¹, Yusuke Eto ¹, Masafumi Fukiage ¹, Akio Nishiura ¹, Soonih Kim ¹, Yuji Miyamoto ¹, Akira Takada ¹ (1.Pharmaceutical Research & Development, ONO Pharmaceutical Co., Ltd., 2.Medicinal Chemistry Research Laboratories, ONO Pharmaceutical Co., Ltd.)

^○Kazuhisa Ozeki ^1,2, Motohiro Kato ¹, Yuuji Sakurai ¹, Masaki Ishigai ¹, Toshiyuki Kudo ², Kiyomi Ito ² (1.Fuji Gotemba Reserch Labs, Chugai pharmaceutical Co., LTD., 2.Research Institute of Pharmaceutical Sciences, Musashino University)

^○Seigo Sanoh ¹, Akihiko Shinagawa ², Akane Doi ², Chihiro Yamasaki ³, Yuji Ishida ³, Masakazu Kakuni ³, Chise Tateno ³, Shigeru Ohta ¹ (1.Graduate School of Biomedical and Health Sciences, Hiroshima University, 2.Faculty of Pharmaceutical Sciences, Hiroshima University, 3.R&D Department, PhoenixBio, Co., Ltd.)

^○Yusuke Kitsugi ¹, Kanami Ikeda ¹, Atsushi Matsuoka ¹, Takaaki Tokunaga ¹, Natsumi Tomida ¹, Haruka Shirosawa ¹, Takahiro Yoshikawa ¹, Yasuhiro Uno ¹, Kazuhide Iwasaki ¹, Masahiro Utoh ¹ (1.Pharmacokinetics and Bioanalysis Center (PBC), Shin Nippon Biomedical Laboratories (SNBL), Ltd., 2.Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University)

^○Koji Chiba , Tomohiko Takatsu , Masahiro Hayashida , Yasuo Shikamoto , Kazuki Terada (Laboratory of Clinical Pharmacology, Yokohama University of Pharmacy)

^○Noriyuki Ishihara ^1,2, Nobuhiro Nishimura ¹, Fumi Karino ³, Kiyotaka Miura ³, Hiroki Tamaki ¹, Takeshi Isobe ³, Kazuro Ikawa ², Norifumi Morikawa ², Kohji Naora ¹ (1.Department of Pharmacy, Shimane University Hospital, 2.Department of Clinical Pharmacotherapy, Graduate School of Biomedical and Health Sciences, Hiroshima University, 3.Department of Internal Medicine, Division of Medical Oncology and Respiratory Medicine, Shimane University Faculty of Medicine)

^○Tomohiro Terada ¹, Daiki Hira ¹, Yugo Chisaki ², Satoshi Noda ¹, Hisazumi Araki ³, Takashi Uzu ³, Hiroshi Maegawa ³, Yoshitaka Yano ², Shin-ya Morita ¹ (1.Department of Pharmacy, Shiga University of Medical Science Hospital, 2.Kyoto Pharmaceutical University, 3.Department of Medicine, Shiga University of Medical Science)

^○Masaki Hattori ¹, Mao Fujita ², Kenta Kono ¹, Hiroyuki Nojima ², Masato Gomi ¹, Ken-ichi Ogawara ¹, Kazutaka Higaki ¹ (1.Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2.Faculty of Pharmaceutical Sciences, Okayama University)

^○Chen-Hsi Chou ¹, Chien-Lung Tu ², Jin-ding Huang ^1,2, Ching-Ling Cheng ³ (1.School of Pharmacy and Institute of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine, National Cheng Kung University, 2.Department of Pharmacology, College of Medicine, National Cheng Kung University, 3.Department of Pharmacy, Chia-Nan University of Pharmacy and Science)

^○Hiroko Shigemizu ¹, Tomonori Takami ², Takayuki Kitano ¹, Shiho Konno ¹, Rieko Goto ¹, Satomi Sasahara ¹, Noriyuki Danno ¹, Noriko Inoue ¹ (1.CMIC Pharma Science Co., Ltd., 2.CMIC, Inc.)

^○Yuichiro Higuchi ¹, Kenji Kawai ¹, Tatsuro Kanaki ², Hiroshi Yamazaki ³, Chesne Cristophe ⁴, Guguen-Guillouzo Christiane ⁴, Hiroshi Suemizu ¹ (1.Central Institute for Experimental Animals, 2.Nissan Chemical Industries, 3.Showa Pharmaceutical University, 4.Biopredic International)

^○Chihiro Yamasaki ¹, Ami Yanagi ¹, Yasumi Yoshizane ¹, Yutaka Kageyama ¹, Yumiko Iwasaki ¹, Yuji Ishida ^1,2, Chise Tateno ^1,2 (1.PhoenixBio Co., Ltd., 2.Liver Research Project Center, Hiroshima University)

^○Keiko Maekawa ¹, Kazuo Okemoto ^1,2, Kazuhisa Takemoto ¹, Katsuko Toyoshima ¹, Masayo Urata ¹, Mayumi Murayama ¹, Masaki Ishikawa ¹, Kosuke Saito ¹, Yuji Kumagai ³, Yoshiro Saito ¹ (1.National Institute of Health Sciences, 2.Graduate School of Pharmaceutical Sciences, Nagoya City University, 3.Clinical Research Center, Kitasato University School of Medicine)