Symposium

Symposium6「UP-to-date trends and advances in clinical pharmacology research using pharmacokinetic information」

Thu. Nov 12, 2015 3:00 PM - 5:30 PM Room B (5ＦＳｍａｌｌＨａｌｌ)

Organizer・Chair:Hideyuki Saito (Department of Pharmacy, Kumamoto University Hospital), Chair:Tomohiro Terada (Department of Pharmacy, Shiga University of Medical Science Hospital)

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[SY-06-01] The PGx & Dose Finding of ARQ197 (Tivantinib), c-Met inhibotor

^○Nobuyuki Yamamoto (Third Department of Internal Medicine, Wakayama Medical University)

[SY-06-02] Development of an S-1 dosage formula based on renal function by a prospective pharmacokinetic study

^○Chiyo K. Imamura (Department of Clinical Pharmacokinetics and Pharmacodynamics, School of Medicine, Keio University)

[SY-06-03] Reduced folate carrier 1 genetic polymorphism and gene expression levels are correlated with methotrexate efficacy in Japanese patients with rheumatoid arthritis

^○Hideki Hayashi ^1,2, Yui Tazoe ², Seiji Tsuboi ³, Taiji Matsuyama ⁴, Tadashi Sugiyama ¹, Kunihiko Itoh ² (1.Laboratory of Pharmacy Practice and Social Science, Gifu Pharmaceutical University, 2.Department of Clinical Pharmacology and Genetics, School of Pharmaceutical Sciences, University of Shizuoka, 3.Department of Rheumatology, Shizuoka Kousei Hospital, 4.Department of Pharmacy, Shizuoka Kousei Hospital)

[SY-06-04] The use of population pharmacokinetic and pharmacodynamic modeling in anti-osteoporotic drug development

^○Chihiro Hasegawa (Clinical Pharmacology, Ono Pharmaceutical Co.,Ltd.)

[SY-06-05] Predicting human hypertension from a comparison of rat and human plasma concentration of VEGFR-2 inhibitors that cause hypertension

^○Taiji Miyake , Motohiro Kato , Koji Yamaguchi , Ryoichi Saitoh , Shinichi Arai , Masaki Ishigai (Research Division, Chugai Pharmaceutical Co., Ltd.)

[SY-06-06] Association of ABCG2 and ABCB1 polymorphisms with plasma concentration of axitinib in patients with renal cell carcinoma

^○Hiroshi Kato ¹, Naoto Sassa ², Masayuki Miyazaki ¹, Mio Takeuchi ³, Miho Asai ³, Akane Iwai ³, Yukihiro Noda ³, Kiyofumi Yamada ¹ (1.Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, 2.Department of Urology, Nagoya University Graduate School of Medicine, 3.Division of Clinical Sciences and Neuropsychopharmacology, Meijo University Faculty of Pharmacy)