Comparison of HepaRG cells with human primary hepatocytes for evaluation of cytochrome P450 induction using 44 drug candidates

Tomoko Kojima

[1-I-P-64] Comparison of HepaRG cells with human primary hepatocytes for evaluation of cytochrome P450 induction using 44 drug candidates

^○Tomoko Kojima ¹, Hiroyuki Moriguchi ², Ju-Young Park ¹, Akihiko Takeuchi ¹, Aiji Miyashita ², Koichi Shiozuka ¹, Kenji Tabata ² (1.Drug Metabolism & Pharmacokinetics Research Div., 2.Analysis & Pharmacokinetics Research Labs, Astellas Pharma Inc.)

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[1-I-P-64] Comparison of HepaRG cells with human primary hepatocytes for evaluation of cytochrome P450 induction using 44 drug candidates

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