Increased sensitivity of human colon cancer cell line HCT-116 to Irinotecan and its active metabolite SN-38 in combination with a DNA methyltransferase inhibitor

Shuko Hakata

[2-H-P-25] Increased sensitivity of human colon cancer cell line HCT-116 to Irinotecan and its active metabolite SN-38 in combination with a DNA methyltransferase inhibitor

^○Shuko Hakata ¹, Wataru Habano ¹, Koji Okada ^1,2, Jun Terashima ¹, Shogo Ozawa ¹ (1.Graduate School of Pharmaceutical and Health Sciences, Iwate Medical University, 2.Department of Pharmacy, Iwate Prefectural Central Hospital)

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[2-H-P-25] Increased sensitivity of human colon cancer cell line HCT-116 to Irinotecan and its active metabolite SN-38 in combination with a DNA methyltransferase inhibitor

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