Predicting hepatotoxic potential of drug candidates using DILIsym, a mechanistic model of DILI

Toshinobu Shimizu

Presentation information

Symposium

Symposium15「Quantitative Systems Pharmacology on Drug Development and Discovery Research」

Sat. Nov 14, 2015 9:30 AM - 12:00 PM Room C (2ＦＴｏｕｇｅｎ-Fukuju)

Organizer:Kenji Tabata(Analysis & Pharmacokinetics Research Labs, Astellas Pharma Inc.), Chairs:Noriko Okudaira(Drug Metabolism & Pharmacokinetics Research Laboratories, R&D Division, Daiichi Sankyo Co., Ltd.), Yuji Kumagai(Kitasato Clinical Research Center), Ryosei Kawai(Clinical Sciences Japan, Bayer Yakuhin, Ltd.), Masayo Oishi(Clinical pharmacology, Pfizer Japan Inc.), Yasuhisa Nagasaka(Pharmacokinetics-Pharmacodynamics, Analysis & Pharmacokinetics Research Labs, Astellas Pharma Inc.), Naomi Nagai(Pharmaceuticals and Medical Devices Agency), Koji Chiba(Laboratory of Clinical Pharmacology, Yokohama University of Pharmacy), Teruki Hamada(Drug Metabolism & Pharmacokinetics Research Laboratories, Takeda Pharmaceutical Company Limited)

[SY-15-01] Predicting hepatotoxic potential of drug candidates using DILIsym, a mechanistic model of DILI

^○Toshinobu Shimizu (Safety Research Laboratories, Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation)

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