Shoko Takeyama ¹, Yoshimine Fujii ¹, Nobuyuki Murayama ¹, Makoto Kataoka ², Masayuki Takahashi ¹, Shinji Yamashita ² (1.DAIICHI SANKYO RD NOVARE CO.,LTD., 2.Faculty of Pharmaceutical Scienes, Setsunan University)

Yosuke Hishikawa, Hiroaki Yuasa, Tomoya Yasujima (Graduate School of Pharmaceutical Sciences, Nagoya City University)

Maria Seki ¹, Yoshiyuki Shirasaka ¹, Marie Hatakeyama ¹, Yuko Kurokawa ¹, Hisanao Kishimoto ¹, Nora Lee ², Joanne Wang ², Katsuhisa Inoue ¹ (1.School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 2.School of Pharmacy, University of Washington)

Norihito Nakata ¹, Yoshinari Shoyama ¹, Akio Hayashi ¹, Atsuko Tsujii ², Shun Hashimoto ², Yuji Ito ² (1.Research Centre, Nihon Medi-Physics Co. Ltd., 2.Graduate School of Science and Engineering, Kagoshima University)

Shigeru Kawakami ¹, Natsuko Oyama ¹, Yuki Fuchigami ¹, Megumu Sato ², Wang Wei ¹, Masayori Hagimori ¹, Shintaro Fumoto ¹ (1.Graduate School of Biomedical Sciences, Nagasaki University, 2.School of Pharmaceutical Sciences, Nagasaki University)

Maki Miyamoto, Shinji Iwasaki, Ikumi Chisaki, Sayaka Nakagawa, Nobuyuki Amano, Hideki Hirabayashi (Drug Metabolism and Pharmacokinetics Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited)

Ryoma Yamamoto, Shigeru Yamada (Thermo Fisher Scientific)

Rui Fujimura ¹, Kento Nishida ¹, Hiroshi Watanabe ^1,2, Masaki Otagiri ^3,4, Toru Maruyama ^1,2 (1.Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Japan, 2.Center for Clinical Pharmaceutical Sciences, School of Pharmacy, Kumamoto University, Japan, 3.Faculty of Pharmaceutical Sciences, Sojo University, Japan, 4.DDS Research Institute, Sojo University, Japan)

Shota Suzuki ¹, Tomomi Furihata ^1,2, Kenta Umehara ¹, Keita Kitamura ¹, Kan Chiba ¹, Naohiko Anzai ², Hidetaka Akita ¹ (1.Graduate School of Pharmaceutical Sciences, Chiba University, 2.Graduate School of Medicine, Chiba University)

Shino Kuramoto, Motohiro Kato, Hidetoshi Shindoh, Masaki Ishigai (Chugai Phamaceutical Co. Ltd, Preclinical Research Dept.)

Harutoshi Kato ^1,2, Noriyuki Yamaotsu ², Norihiko Iwazaki ¹, Shigeaki Okamura ¹, Toshiyuki Kume ³, Shuichi Hirono ² (1.DMPK Research Laboratories, Mitsubishi Tanabe Pharma Corporation, 2.Laboratory of Physical Chemistry for Drug Design, School of Pharmacy, Kitasato University, 3.Discovery Technology Laboratories, Mitsubishi Tanabe Pharma Corporation)

Norie Murayama ¹, Kanako Yajima ^1,2, Mikiko Hikawa ¹, Yuu Ishii ¹, Masaki Takada ¹, Masami Kato ¹, Kanami Shimura ¹, Tomonori Miura ¹, Yasuhiro Uno ², Kazuhide Iwasaki ², Masahiro Utoh ^1,2, Hiroshi Yamazaki ¹ (1.Showa Pharmaceutical University, 2.Shin Nippon Biomedical Laboratories. Ltd.)

Tomoyuki Isobe, Hidetada Shimizu, Masamichi Hirayama, Kimie Nishida, Hiroyuki Kakuo, Yasuhiro Yamato, Yoshikazu Kurahashi, Shin-ichi Miura (Non-Clinical Evaluation Expert Committee, Drug Evaluation Committee, Japan Pharmaceutical Manufacturers Association (JPMA))

Mai Kosaka, Yohei Kosugi, Hideki Hirabayashi (Drug Metabolism and Pharmacokinetics Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited)

Michael B. Bolger, Ke X. Szeto, Viera Lukacova, John DiBella, Walter S. Woltosz (Simulations Plus, Inc.)

Haruka Nishimuta, Takao Watanabe, Kimihiko Sato, Kiyoko Bando, Masashi Yabuki (Preclinical Research Laboratories, Sumitomo Dainippon Pharma Co., Ltd.)

Makoto Ishii, Risa Komatsu, Taihei Sugano, Kaori Morimoto, Mikio Tomita (Department of Drug Absorption and Pharmacokinetics, Tohoku Medical and Pharmaceutical University)

Kensuke Shibakita, Makoto Osabe, Hiroshi Tomiyoshi, Masahiro Tohkin (Regulatory Science, Graduate School of Pharmaceutical Sciences, Nagoya City University)

Masahiro Utoh ^1,2, Takashi Kusama ¹, Tomonori Miura ¹, Marina Mitsui ¹, Mirai Kawano ¹, Takahiro Hirano ^1,2, Makiko Shimizu ¹, Yasuhiro Uno ², Hiroshi Yamazaki ¹ (1.Showa Pharmaceutical University, 2.Shin Nippon Biomedical Laboratories, Ltd.)

Emi Matsuba, Ryutaro Hattori, Shogo Okubo, Miki Fukao, Yukiya Hashimoto (University of Toyama)

Kohei Togami, Anti Kitayama, Hitoshi Tada, Sumio Chono (Hokkaido Pharmaceutical University)

Yutaro Takashima ¹, Gaku Akashita ¹, Tsutomu Shimada ¹, Masumi Ichinose ², Yutaka Yonemura ³, Yoshimichi Sai ¹ (1.Department of Hospital Pharmacy, University Hospital, Kanazawa University, 2.Peritoneal Dissemination Center, Kusatsu General Hospital, 3.NPO Organization to Support Peritoneal Surface Malignancy Treatment)

Tatsuhiko Tachibana, Motohiro Kato, Ryoichi Saito, Masaki Ishigai (Chugai Pharmaceutical Co., Ltd. Pre-Clinical Research Dept.)

Eri Tohyama ¹, Kaori Yasuda ¹, Masashi Takano ², Atsushi Kittaka ², Hiroki Mano ¹, Masaki Kamakura ¹, Shinichi Ikushiro ¹, Miho Ohta ³, Toshiyuki Sakaki ¹ (1.Department of Biology Faculty of Engineering, Toyama Prefectural University, 2.Faculty of Pharmacy Sciences, Teikyo University, 3.Development Nourishment Department, Soai University)

Nobutomo Ikarashi, Sosuke Ogawa, Ryuta Hirobe, Yoshiki Kusunoki, Risako Kon, Wataru Ochiai, Kiyoshi Sugiyama (Department of Clinical Pharmacokinetics, Hoshi University)

Daisuke Inoue ¹, Masahiro Hirao ¹, Akiko Tanaka ², Kosuke Kusamori ², Hidemasa Katsumi ², Akira Yamamoto ², Toshiyasu Sakane ³, Tomoyuki Furubayashi ¹ (1.School of Pharmacy, Shujitsu University, 2.Kyoto Pharmaceutical University, 3.Kobe Pharmaceutical University)

Masakazu Hirouchi ¹, Nobuaki Watanabe ¹, Masakazu Kakuni ², Taro Okada ², Osamu Ando ¹ (1.DAIICHI SANKYO CO., LTD, 2.PhoenixBio Co., Ltd.)

Erina Yamazaki ¹, Yusuke Masuo ¹, Ken-ichi Fujita ², Toshiki Shibutani ¹, Noritaka Nakamichi ¹, Yasutsuna Sasaki ², Yukio Kato ¹ (1.Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 2.Institute of Molecular Oncology, Showa University)

Tatsuki Mochizuki, Tadahaya Mizuno, Hiroyuki Kusuhara (Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, the University of Tokyo)

Tomohiro Yoshida, Tatsuki Fukami, Saki Gotoh, Miki Nakajima (Faculty of Pharmaceutical Sciences, Kanazawa University)

Aoi Hasegawa ¹, Yusuke Masuo ¹, Shushi Nagamori ², Kazuki Hayashi ¹, Noritaka Nakamichi ¹, Yoshikatsu Kanai ², Yukio Kato ¹ (1.Faculty of Pharmacy, Kanazawa University, 2.Graduate School of Medicine, Osaka University)

Daisuke Satoh ¹, Satoru Iwado ², Jiro Kuze ^1,3, Kaoru Kobayashi ⁴, Mitsuhiko Osaki ^1,2, Shoko Takehara ¹, Igarashi Katsuhide ⁵, Satoshi Kitajima ⁶, Jun Kanno ^6,7, Kan Chiba ⁴, Mitsuo Oshimura ¹, Yasuhiro Kazuki ^1,2 (1.Chromosome Engineering Research Center, 2.Graduate School of Medical Sciences, Tottori University, 3.Taiho Pharmaceutical Co., Ltd, 4.Graduate School of Pharmaceutical Sciences, Chiba University, 5.Hoshi University, 6.National Institute of Health Sciences, 7.Japan Organization of Occupational Health and Safety)

Robert D. Clark, David Miller, Michael S. Lawless, Marvin Waldman, Walter S. Woltosz (Simulations Plus, Inc)

Jo Hatogai, Wataru Ochiai, Satoshi Kitaoka, Nanako Niikura, Miho Hirata, Nanako Fukasawa, Satoru Miyazaki, Naoto Yamaguchi, Nobutomo Ikarashi, kiyoshi Sugiyama (Department of Clinical Pharmacokinetics Hoshi University)

Chihiro Yamasaki ¹, Ami Yanagi ¹, Yasumi Yoshizane ¹, Yutaka Kageyama ¹, Yumiko Iwasaki ¹, Yuji Ishida ^1,2, Seiichi Ishida ³, Chise Tateno ^1,2 (1.PhoenixBio Co., Ltd., 2.Liver Research Project Center, Hiroshima University, 3.Division of Pharmacology, National Institute of Health Sciences)

Masato Takahashi, Kenta Mizoi, Masami Haba, Masakiyo Hosokawa (Faculty of Pharmacy, Chiba Institute of Science)

Yasuhiro Uno ¹, Norie Murayama ², Masahiro Utoh ¹, Hiroshi Yamazaki ² (1.Shin Nippon Biomedical Laboratories, 2.Showa Pharmaceutical University)

Ayumi Kurita ¹, Yuu Miyauchi ¹, Peter I. Mackenzie ², Hideyuki Yamada ¹, Yuji Ishii ¹ (1.Graduate school of Pharmaceutical Sciences, Kyushu University, 2.Department of Clinical Pharmacology, Flinders University)

Itsuki Nakano, Miki Katoh, Yuki Asai, Masayuki Nadai (Faculty of Pharmacy, Meijo University)

Tsutomu Sakuma, Akiko Kubota, Shinpei Endo, Ami Minatoyama, Yuji Motegi, Yuka Izumi, Yuki Kawasaki, Nobuo Nemoto, Hiroaki Sakurai (Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama)

Yasuhiro Masubuchi, Shinji Kondo (Faculty of Pharmaceutical Sciences, Chiba Institute of Science)

Akira Okada, Shunsuke Marufuji, Mana Nakanishi, Mai Fujita, Hiroyuki Oe, Mika Hirasaki, Keizo Fukushima, Nobuyuki Sugioka (Department of Clinical Pharmacokinetics, Faculty of Pharmaceutical Sciences, Kobe Gakuin University)

Yosuke Iyama, Hiroto Ohtake, Hideyuki Sato, Yoshiki Seto, Satomi Onoue (Department of Pharmacokinetics and Pharmacodynamics, School of Pharmaceutical Sciences, University of Shizuoka)

Yasuhiro Yamato ¹, Falgun Shah ² (1.Drug Safety Research & Development, Pfizer Japan, 2.Computational Science CoE (WWMC), Pfizer, Groton)

Hiroshi Watanabe ¹, Yuki Enoki ¹, Riho Arake ¹, Motoko Tanaka ², Masafumi Fukagawa ³, Masaki Otagiri ⁴, Toru Maruyama ¹ (1.Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 2.Department of Nephrology, Akebono Clinic, 3.Division of Nephrology, Endocrinology and Metabolism, Tokai University School of Medicine, 4.Faculty of Pharmaceutical Sciences, Sojo University)

Shuichi Sekine ¹, Moemi Kawaguchi ¹, Takumi Nukaga ¹, Takeshi Susukida ¹, Akinori Takemura ¹, Cong Liu ¹, Morihiko Hirota ², Shiho Oeda ², Akiko Tamura ², Nana Kuwata ², Hirokazu Kouzuki ², Kousei Ito ¹ (1.Laboratoy of Biopharmaceutics, Graduate school of Pharmaceutical Sciences, Chiba University, 2.Shiseido Global Innovation Center)

Cong Liu, Shuichi Sekine, Kousei Ito (Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University)

Ryota Hashimoto, Atsushi Kawase, Mai Shibata, Hiroaki Shimada, Masahiro Iwaki (Faculty of Pharmacy, Kindai University)

Sota Fujimori, Shigeki Aoki, Kousei Ito (Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University, Japan)

Masayuki Masuda ^1,2, Kazuaki Sugio ¹, Toru Masaka ², Kazumi Shimono ¹, Seiji Miyauchi ¹ (1.Faculty of Pharmaceutical Sciences, Toho University, 2.Department of Pharmacy, Toho University Sakura Medical Center)

Yoshiyuki Kubo, Shizuka Yahata, Satoshi Miki, Shin-ichi Akanuma, Ken-ichi Hosoya (University of Toyama)

Hiroki Ito, Saki Toyota, Ryoko Yumoto, Mikihisa Takano (Graduate School of Biomedical & Health Sciences, Hiroshima University)

Ryosuke Naka, Saori Nishimoto, Ryoko Yumoto, Mikihisa Takano (Graduate School of Biomedical & Health Sciences, Hiroshima University)

Yuki Yamasaki ¹, Kaoru Kobayashi ¹, Satoshi Abe ², Naoyo Kajitani ², Kanako Kazuki ², Shoko Takehara ², Fuka Okuya ¹, Shingo Ito ^3,4, Seiryo Ogata ³, Sumio Ohtsuki ^3,4, Hidetaka Akita ¹, Kan Chiba ¹, Mitsuo Oshimura ², Yasuhiro Kazuki ^2,5 (1.Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University, 2.Chromosome Engineering Research Center, Tottori University, 3.School of Pharmacy, Kumamoto University, 4.Faculty of Life Sciences, Kumamoto University, 5.Graduate School of Medical Science, Tottori University)

Kentaro Yano ¹, Saori Shimizu ¹, Takuo Ogihara ² (1.Laboratory of biopharmaceutics, Faculty of Pharmacy, Takasaki University of Health and Welfare, 2.Laboratory of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Takasaki University of Health and Welfare)

Kanako Furugori, Saki Noguchi, Hiromi Shinohara, Makiko Abe, Tomohiro Nishimura, Emi Nakashima, Masatoshi Tomi (Faculty of Pharmacy, Keio University)

Natsumi Seba ¹, Yusuke Masuo ¹, Ken-ichi Fujita ², Noritaka Nakamichi ¹, Yasutsuna Sasaki ², Yukio Kato ¹ (1.Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 2.Institute of Molecular Oncology, Showa University)

Yuta Inoue, Atsushi Kawase, Sayaka Nakazaki, Erika Koizumi, Hiroaki Shimada, Masahiro Iwaki (Faculty of Pharmacy, Kindai University)

Risako Kon ^1,2, Hiroshi Kimura ², Yukari Matsunaga ², Moe Minami ², Saki Kato ², Nobutomo Ikarashi ² (1.Global Research Center for Innovative Life Science, Hoshi University, 2.Department of Clinical Pharmacokinetics, Hoshi University)

Yurika Miki, Ryusuke Iwai, Hisakazu Komori, Daichi Fujita, Takeo Nakanishi, Izumi Tamai (Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University)

Yusuke Masuo, Hiro Takemura, Mai Matsuo, Noritaka Nakamichi, Yukio Kato (Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University)

Takeshi Sakata ¹, Viktória Juhász ¹, Erzsébet Beéry ¹, Zsuzsanna Gáborik ¹, Zsolt Fekete ¹, Colin Brown ², Joe Zolnerciks ³ (1.SOLVO Biotechnology, Budaörs, Hungary, 2.Institute for Cell & Molecular Bioscience Medical School Newcastle University, Newcastle, United Kingdom, 3.SOLVO Biotechnology USA, Seattle, WA)

Hiroaki Shimada ¹, Yuichi Urabe ¹, Yuhei Okamoto ¹, Mayumi Komura ¹, Yuki Yamashita ¹, Atsushi Kawase ¹, Toshio Morikawa ², Osamu Muraoka ², Masahiro Iwaki ¹ (1.Department of Pharmacy, Faculty of Pharmacy, Kindai University, 2.Pharmaceutical Research and Technology Institute, Kindai University)

Daichi Onozato ¹, Takumi Akagawa ², Misaki Yamashita ², Yuriko Kida ², Akiko Koeda ¹, Takahiro Iwao ^1,2, Tamihide Matsunaga ^1,2 (1.Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, 2.Educational Research center for Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Nagoya City University)

Taku Onishi ¹, Daichi Onozato ¹, Takahiro Iwao ¹, Shinji Sakai ², Masahito Taya ², Tamihide Matsunaga ¹ (1.Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, 2.Division of Chemical Engineering, Department of Materials Science and Engineering, Graduate School of Engineering Science, Osaka university)

Misaki Yamashita ¹, Daichi Onozato ², Takumi Akagawa ¹, Takahiro Iwao ^1,2, Tamihide Matsunaga ^1,2 (1.Educational Research center for Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Nagoya City University, 2.Department of Clinical Pharmacy, Graduate School of Pharmaseutical Sciences, Nagoya City University)

Keishi Yamasaki ^1,2, Taisuke Enokida ¹, Akito Kawai ¹, Shuichi Miyamoto ¹, Kazuaki Taguchi ¹, Toru Maruyama ³, Hakaru Seo ^1,2, Masaki Otagiri ^1,2 (1.Faculty of Pharmaceutical Sciences, Sojo University, 2.DDS Research Institute, Sojo University, 3.Graduate School of Pharmaceutical Sciences, Kumamoto University)

Masaki Takeuchi ¹, Shingo Oda ¹, Koichi Tsuneyama ², Tsuyoshi Yokoi ¹ (1.Laboratory of Drug Safety Sciences, Division of Clinical Pharmacology, Nagoya University Graduate School of Medicine, 2.Department of Pathology and Laboratory Medicine, Institute of Biomedical Sciences Tokushima University Graduate School)