Oral

[O1-3] Filovirus

Sun. Nov 13, 2022 1:50 PM - 3:20 PM Room 3 (Conference Room 103)

Chair:
Yasuteru Sakurai(Nagasaki University)
Ayato Takada(International Institute for Zoonosis Control, Hokkaido University)

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1:50 PM - 2:05 PM

[O1-3-1] Development of an imaging system for the Ebola virus glycoprotein throughout viral life cycle

*Wakako Furuyama¹, Miako Sakaguchi², Kento Yamada¹, Asuka Nanbo¹ (1. National Research Center for the Control and Prevention of Infectious Diseases, Nagasaki University, 2. Central Laboratory, Institute of Tropical Medicine (NEKKEN), Nagasaki University)

2:05 PM - 2:20 PM

[O1-3-2] Ebola virus exploits clathrin coated vesicle transport pathway for viral particle formation

*ASUKA NANBO¹, Michiko Ujie², Takeshi Saito³, Wakako Furuyama¹, Yoichiro Fujioka³, Sayaka Kashiwagi³, Peter Halfmann⁴, Masaki Imai², Ayato Takada³, Yusuke Ohba³, Yoshihiro Kawaoka^2,4,5 (1. Nagasaki University, 2. University of Tokyo, 3. Hokkaido University, 4. University of Wisconsin-Madison, 5. National Center for Global Health and Medicine)

2:20 PM - 2:35 PM

[O1-3-3] Revealing the molecular mechanisms of filovirus particle formation focusing on VP30

*Yuki Takamatsu^1,2,3, Takeshi Noda², Stephan Becker³ (1. Nagasaki University, 2. Kyoto University, 3. Philipps University Marburg)

2:35 PM - 2:50 PM

[O1-3-4] Establishment of iPS-derived vascular endothelial cells to evaluate cellular damage caused by Ebola virus infection

*Murasaki Amano^1,2,3, Yasuteru Sakurai^1,3, Keiko Imamura^4,5,6, Takayuki Kondo^4,5,6, Haruhisa Inoue^4,5,6, Jiro Yasuda^1,2,3 (1. Department of Emerging Infectious Diseases, National Research Center for the Control and Prevention of Infectious Diseases (CCPID), Nagasaki University, 2. Graduate School of Biomedical Sciences, Nagasaki University, 3. Institute of Tropical Medicine (NEKKEN), Nagasaki University, 4. Center for iPS Cell Research and Application (CiRA), Kyoto University, 5. iPSC-Based Drug Discovery and Development Team, RIKEN BioResource Research Center (BRC), 6. Medical-risk Avoidance based on iPS Cells Team, RIKEN Center for Advanced Intelligence Project (AIP))

2:50 PM - 3:05 PM

[O1-3-5] Identification of novel compounds inhibiting Ebola virus infection through depletion of the intracellular pyrimidine pool

*Christelle Mawonga Pemba¹, Yasuteru Sakurai^1,2, Yohei Kurosaki², Daniel Ken Inaoka^3,5, Kiyoshi Kita^4,5, Jiro Yasuda^1,2 (1. Department of Emerging Infectious Diseases, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 2. National Research Center for the Control and Prevention of Infectious Diseases, Nagasaki University, 3. Department of Molecular Infection Dynamics, Shionogi Global Infectious Diseases Division, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 4. Department of Host - Defense Biochemistry, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 5. School of Tropical Medicine and Global Health, Nagasaki University)

3:05 PM - 3:20 PM

[O1-3-6] Development of anti-Ebola virus drug candidates using a unique peptidomimetic technology

*Yasuteru Sakurai¹, Christelle M. Pemba¹, Kazuo Kurosawa², Tadashi Mishina², Thomas Hoenen³, Robert A. Davey⁴, Hiroyuki Koji², Jiro Yasuda¹ (1. Nagasaki University, 2. Oita University Institute of Advanced Medicine, Inc, 3. Friedrich-Loeffler-Institut, 4. Boston University)

Session information