The year 2016 is the 100th anniversary of the birth of Francis Crick, the greatest biologist in the 20th century. Molecular biology has advanced after the discovery of the DNA double helix. The life of Francis Crick, who always created new concepts by discovering the genetic code and also by contributing to brain science etc., was with the creation of molecular biology. In this symposium, we will try to review the phenomenon of life from DNA to brain, which Crick paved the way, and to consider the molecular biology in the future.