The Molecular Biology Society of Japan

[1P-0042] Elucidation of structural mechanism for inhibition of a voltage-gated potassium ion channel, hERG1, by a gating modifier toxin, APETx1.

〇Kazuki Matsumura1, Masahiro Fukuda1, Naomi Yanase1, Madoka Akimoto1, Nanami Iwasaki2, Kazuho Sakamoto2, Junko Kurokawa2, Mariko Yokogawa1, Masanori Osawa1 (1.Keio Univ. Grad. Sch. Pharm. Sci., 2.Univ. of Shizuoka Sch. Pharm. Sci.)

Voltage-gated potassium ion channel, hERG1, Voltage sensing domain, APETx1, Structural analysis

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