[3P-0075(3AW-07-5)] Structural basis of stabilization mechanism of LUBAC, a ligase for linear-ubiquitination

〇Akira Tokunaga¹, Hiroaki Fujita², Erik Walinda², Izuru Ohki¹, Mariko Ariyoshi³, Hidehito Tochio⁴, Kazuhiro Iwai², Masahiro Shirakawa¹ (1.Dept of Mol Eng, Grad Sch of Eng, Univ of Kyoto, 2.Dept of Med Sci, Grad Sch of Med, Univ of Kyoto, 3.Grad Sch of Frontier Biosci, Univ of Osaka, 4.Dept of Biol Sci, Grad Sch of Sci, Univ of Kyoto)

LUBAC, HOIP, HOIL-1L, SHARPIN, linear ubiquitin chains