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Thu. May 24, 2018 8:00 AM - 9:40 AM Room 1 (Sapporo Geibunkan / Nitori Culture Hall （1F）)
Chair: Mikio Shoji(Department of Neurology, Hirosaki University Graduate School of Medicine, Japan), Hiroshi Mori(Dept of Clinical Neuroscience, Osaka City University Medical school/Tamiya Hospital, Japan)
Japan Society for Dementia Research
To verify the natural course and effects of disease modyfing therapy of Alzheimer's disease, many cohort studies are now ongoing. DIAN and preclinical AD study are outstanding observation study of preclinical and symptpmatic stages oif AD. A4 and DIAN-TU are prominent clinical trials of anti-Aß antibodes for autosomal dominantly inherited AD and Amyloid PET positive sporadic AD. Here we provide most advanced findings of these cohort studies and reserches and discuss prospective development for disease modifying therapies.
○Mie Hirohata (Department of Neurology, Institute of Brain Science, Hirosaki University Graduate School of Medicine, Japan)
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○Takeshi Iwatsubo (The University of Tokyo, Neuropathology, Unit for Early and Exploratory Clinical Development, Japan)
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○Hiroshi Mori (Dept of Clinical Neuroscience, Osaka City University Medical school/Tamiya Hospital, Japan)
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○Randall Bateman (Washington University is St. Louis School of Medicine, USA)
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