Symposium

[S-23] New fronteer of epileptogenicity: translatability between basic and clinical fields

Fri. May 25, 2018 8:00 AM - 9:30 AM Room 8 (Royton Sapporo / Empress Hall （2F）)

Chair: Akio Ikeda(Department of Epilepsy, Movement Disorders and Physiology Kyoto University Graduate School of Medicine, Japan), Kazutaka Jin(Department of Epileptology, Tohoku University Graduate School of Medicine, Japan)

The Japan Epilepsy Society

Epileptogenicity has not been fully delineated but recently the role of abnormality of AMPA receptor and the glia in the chronic epileptogenicity were extensively studied in both basic and clinical fields and mutual translatability is one of the most active discussions. The both fields, i.e., AMPA receptor and glia, are extensively studied in Japan and are currently lead to the clinical application. All of those discussions will open the new window to the new treatment of epilepsy.

+Add all to schedule

[S-23-1] Characterization of epileptogenic astrocytes

^○Schuichi Koizumi¹, Fumikazu Sano² (1.Dept Neuropharmacol, Interdisciplinary Grad Sch Med, Univ Yamanashi, Japan, 2.Dept Pediatrics, Interdisciplinary Grad Sch Med, Univ Yamanashi, Japan)

[S-23-2] Glia and epileptogenicity from the clinical approach

^○Akio Ikeda (Department of Epilepsy, Movement Disorders and Physiology Kyoto University Graduate School of Medicine, Japan)

[S-23-3] A novel PET tracer for AMPA receptors to visualize epileptic focus

^○Takuya Takahashi (Department of Physiology, Yokohama City University, School of Medicine, Japan)

[S-23-4] Antagonists of AMPA receptor on epilepsy: from clinical point of view

^○Kiyohito Terada (NHO Shizuoka Institute of Epilepsy and Neurological Disorders, Japan)

[S-23-5] Very small dose of perampanel improved refractory cortical myoclonus

^○Kazuki Oi¹, Katsuya Kobayashi¹, Takefumi Hitomi², Shuichiro Neshige¹, Akihiro Shimotake³, Daiki Fujii⁴, Riki Matsumoto¹, Shuhei Kasama⁵, Masutaro Kanda⁶, Yoshiaki Wada⁷, Ryosuke Takahashi¹, Akio Ikeda³ (1.Department of Neurology. Kyoto University Graduate School of Medicine, Japan, 2.Department of Laboratory Medicine. Kyoto University Graduate School of Medicine, Japan, 3.Department of Epilepsy, Movement Disorders and Physiology. Kyoto University Graduate School of Medicine., Japan, 4.Department of Neurology. Kurashiki Central Hospital, Japan, 5.Department of Neurology. Hyogo College of Medicine., Japan, 6.Department of Neurology. Takeda General Hospital., Japan, 7.Department of Rehabilitation. Nissan Tamagawa Hospital., Japan)