[HT-07-3] エンドソーム経路：シヌクレイノパチーにおけるプリオン様伝播現象の分子基盤
Dr. Hasegawa received his M.D. in 1995 and Ph.D. in 2000 from Tohoku Univ. In dissertation research, he successfully isolated ganglioside hydrolyzing sialidase cDNA from mouse brain and discovered its role in neurite formation at Dept Biochemistry, Miyagi Cancer Center, Sendai, Japan (Dr. Taeko Miyagi's Lab). From 2006 to 2008, Dr. Hasegawa joined Dr. Philipp Kahle's Lab as an Alexander von Humboldt fellow in Hertie-Institute, University Clinics Tübingen, Germany, where he studied the protective role of parkin, a causative protein for ARJP (PARK2), against oxidative stress and the mitochondria genome integrity. Currently, he serves as the PI of Parkinson Research Group in Dept Neurol, Tohoku Univ Sch Med. His primary research interest is the functional roles of membrane trafficking in the pathogenesis of Parkinson's disease (PD). In addition, Dr. Hasegawa's group are devoted to establish novel surrogate markers including amyloid PET imaging in PD and other related disorders.
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