[S-29] Alzheimer's disease up to date

[S-29-3] Generation of mutant presenilin 1 mice using a novel RNA-guided base editing technology

^○Hiroki Sasaguri^1,2, Misaki Sekiguchi¹, Ryo Fujioka¹, Kenichi Nagata¹, Takaomi Saido¹ (1.RIKEN Center for Brain Science, Japan, 2.Department of Neurology and Neurological Science, Graduate School of Medicine, Tokyo Medical and Dental University, Japan)

1993 – 1999 Tokyo Medical and Dental University, Faculty of Medicine
1999 – 2000 Resident, Tokyo Medical and Dental University, Medical Hospital
2000 – 2001 Resident, Yokosuka Kyosai Hospital
2001 – 2002 Department of Neurology and Neurological Science, Tokyo Medical and Dental University, Medical Hospital
Department of Neurology, Saitama Rehabilitation Center
2002 – 2004 Department of Neurology, Asahi General Hospital
2004 – 2005 Department of Neurology, Kanto Central Hospital
2005 – 2009 Graduate Student, Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University
2009 – 2012 Department of Neurology, Saitama Rehabilitation Center
2012 – 2014 Department of Neuroscience, Mayo Clinic, Jacksonville (Prof. Petrucelli)
2014 – 2016 Department of Neurology, Nitobe Memorial Nakano General Hospital
2016 to present Research fellow, Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science
Department of Neurology and Neurological Science, Tokyo Medical and Dental University