第60回日本神経学会学術大会

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[HT-10] Motor neuron diseases in the era after translational research

2019年5月25日(土) 08:00 〜 10:00 第4会場 (大阪国際会議場10F 会議室1001-1002)

座長：漆谷 真（国立大学法人 滋賀医科大学内科学講座 脳神経内科）, 佐橋 健太郎（名古屋大学医学部脳神経内科）

A recent advance in understanding the pathogenesis of various motor neuron diseases has lead to groundbreaking therapies for motor neuron diseases, including spinobulbar muscular atrophy and spinal muscular atrophy. In ALS, the antisense oligonucleotide therapy and high thruput drug screening using iPS attract huge attention as a promising therapy. This symposium is focussing on therapeutic advances based on the recent innovative translational researches.

[HT-10-1] 球脊髄性筋萎縮症における神経筋変性の分子メカニズム

飯田 円 (名古屋大学大学院医学系研究科　神経内科学)

A recent advance in understanding the pathogenesis of various motor neuron diseases has lead to groundbreaking therapies for motor neuron diseases, including spinobulbar muscular atrophy and spinal muscular atrophy. In ALS, the antisense oligonucleotide therapy and high thruput drug screening using iPS attract huge attention as a promising therapy. This symposium is focussing on therapeutic advances based on the recent innovative translational researches.

[HT-10-2] Pathogenesis and Therapy of Spinal Muscular Atrophy

Yuh-Jyh Jong1,2,3 (1.Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Taiwan, 2.Departments of Pediatrics and Laboratory Medicine, Kaohsiung Medical University Chung-Ho Memorial Hospital, Taiwan, 3.College of Biological Science and Technology, National Chiao Tung University, Taiwan)

A recent advance in understanding the pathogenesis of various motor neuron diseases has lead to groundbreaking therapies for motor neuron diseases, including spinobulbar muscular atrophy and spinal muscular atrophy. In ALS, the antisense oligonucleotide therapy and high thruput drug screening using iPS attract huge attention as a promising therapy. This symposium is focussing on therapeutic advances based on the recent innovative translational researches.

[HT-10-3] 核酸医薬によるALSの根本治療

横田 隆徳 (東京医科歯科大学病院 脳神経病態学分野)

A recent advance in understanding the pathogenesis of various motor neuron diseases has lead to groundbreaking therapies for motor neuron diseases, including spinobulbar muscular atrophy and spinal muscular atrophy. In ALS, the antisense oligonucleotide therapy and high thruput drug screening using iPS attract huge attention as a promising therapy. This symposium is focussing on therapeutic advances based on the recent innovative translational researches.

[HT-10-4] iPS細胞技術を用いたALSの病態解析と創薬・治験

岡野 栄之 (慶應義塾大学医学部 生理学教室)

A recent advance in understanding the pathogenesis of various motor neuron diseases has lead to groundbreaking therapies for motor neuron diseases, including spinobulbar muscular atrophy and spinal muscular atrophy. In ALS, the antisense oligonucleotide therapy and high thruput drug screening using iPS attract huge attention as a promising therapy. This symposium is focussing on therapeutic advances based on the recent innovative translational researches.