第60回日本神経学会学術大会

セッション情報

印刷

Neuroscience Frontier Symposium

[NFS-01] Frontier of repeat disease

2019年5月23日(木) 08:00 〜 09:30 第6会場 (大阪国際会議場10F 会議室1009)

座長：戸田 達史（東京大学大学院医学系研究科・神経内科学）, 小野寺 理（新潟大学脳研究所神経内科学分野）

Among the hereditary neurodegenerative diseases in past decades, an expansion of the number of triplet repeat sequences has been identified as a causative mutation. However, very recently, an expansion of a number of Penta- and hexa-repeat related diseases have been identified in spinocerebellar ataxia, ALS, and epilepsy. In this symposium, we invited pioneers of these findings. The audience will be able to touch on the forefront of the molecular pathogenesis of new mechanism of neurological disorders.

[NFS-01-1] 良性成人型家族性ミオクローヌスてんかんの分子病態

石浦 浩之 (東京大学病院 神経内科)

Among the hereditary neurodegenerative diseases in past decades, an expansion of the number of triplet repeat sequences has been identified as a causative mutation. However, very recently, an expansion of a number of Penta- and hexa-repeat related diseases have been identified in spinocerebellar ataxia, ALS, and epilepsy. In this symposium, we invited pioneers of these findings. The audience will be able to touch on the forefront of the molecular pathogenesis of new mechanism of neurological disorders.

[NFS-01-2] SCA31の病態

石川 欽也 (東京医科歯科大学病院 長寿・健康人生推進センター)

Among the hereditary neurodegenerative diseases in past decades, an expansion of the number of triplet repeat sequences has been identified as a causative mutation. However, very recently, an expansion of a number of Penta- and hexa-repeat related diseases have been identified in spinocerebellar ataxia, ALS, and epilepsy. In this symposium, we invited pioneers of these findings. The audience will be able to touch on the forefront of the molecular pathogenesis of new mechanism of neurological disorders.

[NFS-01-3] Mechanistic and Therapeutic Insights into Repeat Expansions Disorders

Leonard Petrucelli (Mayo Clinic)

Among the hereditary neurodegenerative diseases in past decades, an expansion of the number of triplet repeat sequences has been identified as a causative mutation. However, very recently, an expansion of a number of Penta- and hexa-repeat related diseases have been identified in spinocerebellar ataxia, ALS, and epilepsy. In this symposium, we invited pioneers of these findings. The audience will be able to touch on the forefront of the molecular pathogenesis of new mechanism of neurological disorders.