Hiroyuki Murai¹, Akiyuki Uzawa², Yasushi Suzuki³, Tomihiro Imai⁴, Hirokazu Shiraishi⁵, Hidekazu Suzuki⁶, Meinoshin Okumara⁷, Fanny O'brien⁸, Jing-jing Wang⁸, Kenji Fujita⁸, Kimiaki Utsugisawa⁹ (1.Department of Neurology, International University of Health and Welfare, 2.Graduate School of Medicine and School of Medicine, Chiba University, 3.National Hospital Organisation Sendai Medical Center, Sendai, 4.Sapporo Medical University Hospital, 5.Nagasaki University Hospital, 6.Ikuwakai Memorial Hospital, 7.Toneyama National Hospital, 8.Alexion Pharmaceuticals, 9.Hanamaki General Hospital)

Nobutaka Hattori¹, Yoshio Tsuboi², Akihiko Yamamoto³, Yuji Sasagawa³, Masahiro Nomoto⁴ (1.Department of Neurology, Juntendo University School of Medicine, 2.Department of Neurology, Fukuoka University School of Medicine, 3.Meiji Seika Pharma Company Limited, 4.Department of Neurology and Clinical Pharmacology, Ehime University Graduate School of Medicine/Saiseikai Imabari Hospital)

Kyoko Higashida¹, Shuhei Okazaki¹, Kenichi Todo¹, Tsutomu Sasaki¹, Nobuyuki Ohara², Takeshi Yoshimoto³, Masatoshi Koga³, Masafumi Ihara³, Shiro Yamamoto⁴, Kazuo Hashikawa⁴, Nobuo Kohara², Hideki Mochizuki¹ (1.Department of Neurology, Osaka University Graduate School of Medicine, 2.Department of Neurology, Kobe City Medical Center General Hospital, 3.Department of Stroke and Cerebrovascular Disease, National Cerebral and Cardiovascular Center, 4.Division of Stroke Medicine, National Hospital Organization Osaka National Hospital)

Ryosuke Oki¹, Yuishin Izumi¹, Hiroyuki Nodera¹, Yasutaka Sato², Hiroshi Nokihara², Hiroaki Yanagawa², Satoshi Kuwabara³, Ryuji Kaji⁴, JETALS collaborators⁵ (1.Department of Clinical Neuroscience, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan., 2.Clinical Trial Center for Developmental Therapeutics, Tokushima University Hospital, Tokushima, Japan., 3.Department of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan, 4.Utano National Hospital, National Hospital Organization, Kyoto, Japan., 5.JETALS collaborators)

Eiichi Nomura^1,2, Tomohiko Ohshita³, Hiromitsu Naka⁴, Hayato Matsushima⁵, Satoshi Kubo⁶, Eiji Imamura⁵, Tsuyoshi Torii⁷, Naohisa Hosomi³, Hirofumi Maruyama³, Masayasu Matsumoto⁸ (1.Department of Neurology, Hiroshima City Hiroshima Citizens Hospital, 2.Department of Neurology, Brain Attack Center Ota Memorial Hospital, 3.Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical and Health Sciences, 4.Department of Neurology, Hiroshima Prefectural Hospital, 5.Department of Neurology, Suiseikai Kajikawa Hospital, 6.Department of Neurology, Chugoku Rosai Hospital, 7.Department of Neurology, National Hospital Organization Kure Medical Center, 8.Sakai City Medical Center)

Kyoko Saida^1,2,3, Takahiko Saida^1,2, Qi Hao^1,2, Michiko Yamauchi^1,2 (1.Kansai Multiple Sclerosis Center, 2.Irino Clinic, 3.Kyoto Hakuaikai Hospital)