Hiroaki Yokote^1,2, Ryota Amano¹, Shuta Toru¹, Takaaki Hattori², Yoichiro Nishida², Nobuo Sanjo², Takanori Yokota² (1.Department of Neurology, Nitobe Memorial Nakano General Hospital, Japan, 2.Department of Neurology and Neurological Sciences, Tokyo Medical and Dental University, Japan)

Tokunori Ikeda^1,2, Tatsuyuki Kakuma³, Eri Watari^2,4, Yukio Ando² (1.Department of Clinical Investigation, Kumamoto University Hospital, Japan, 2.Department of Neurology, Graduate School of Medical Sciences, Kumamoto University, Japan, 3.Department of Biostatics Center, Kurume University, Japan, 4.Fukuoka Mirai Hospital, Japan)

Takahiro Wakasugi, Etsuji Saji, Fumihiro Yanagimura, Mariko Hokari, Kaori Yanagawa, Masatoyo Nishizawa, Osamu Onodera, Izumi Kawachi (Department of Neurology, Brain Research Institute, Niigata University, Japan)

Peng Sun, Xin Shi, Wei Liang, Zhirong Jia (Peking University,Peking University First Hospital, China)

Noriko Isobe¹, Fumie Hayashi², Davide Cossu³, Kazumasa Yokoyama³, Guzailiayi Maimatijiang², Yuri Nakamura², Takuya Matsushita², Nobutaka Hattori³, Jun-ichi Kira² (1.Department of Neurological Therapeutics, Kyushu University, Japan, 2.Department of Neurology, Kyushu University, 3.Department of Neurology, Juntendo Unversity School of Medicine)