60th Annual Meeting of the Japanese Society of Neurology

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Symposium

[S-28] New concepts of glia and brain homeostasis: key missing pieces in the puzzle of neurological disorders

Fri. May 24, 2019 1:45 PM - 3:45 PM Room 7 (Osaka International Convention Center 10F Conference Room 1008)

Chair:Koji Yamanaka(Research Institute of Environmental Medicine, Nagoya University, Japan), Makoto Higuchi(National Institutes for Quantum and Radiological Science and Technology, Japan)

During the last few years, novel concepts of glia and glymphatic system have dramatically yielded unexpected results that challenge the traditional view of neurological disorders including Alzheimer's disease and other neurodegenerative diseases. They also play a crucial role in maintaining brain homeostasis. This symposium will highlight the latest developments in the reserch of glia and glymphatic system for the CNS in health and disease.

[S-28-1] Overview: glia as therapeutic targets for neurodegenerative diseases

Koji Yamanaka (Research Institute of Environmental Medicine, Nagoya University, Japan)

During the last few years, novel concepts of glia and glymphatic system have dramatically yielded unexpected results that challenge the traditional view of neurological disorders including Alzheimer's disease and other neurodegenerative diseases. They also play a crucial role in maintaining brain homeostasis. This symposium will highlight the latest developments in the reserch of glia and glymphatic system for the CNS in health and disease.

[S-28-2] Regulatory T cell modulation of neuroinflammation and progression in amyotrophic lateral sclerosis

Bradley Turner1, Rebecca Sheean1, Fiona Mckay2, Erika Cretney3, Christopher Bye1, Nirma Perera1, Doris Tomas1, Stephen Nutt3, Matthew Kiernan4, Steve Vucic2 (1.Florey Institute of Neuroscience and Mental Health, University of Melbourne, Australia, 2.Westmead Institute for Medical Research, University of Sydney, Australia, 3.Walter and Eliza Hall Institute of Medical Research, Australia, 4.Brain and Mind Centre, University of Sydney, Australia)

During the last few years, novel concepts of glia and glymphatic system have dramatically yielded unexpected results that challenge the traditional view of neurological disorders including Alzheimer's disease and other neurodegenerative diseases. They also play a crucial role in maintaining brain homeostasis. This symposium will highlight the latest developments in the reserch of glia and glymphatic system for the CNS in health and disease.

[S-28-3] Reactive Astrocytes, MAO-B, GABA, Hydrogen Peroxide, and Alzheimer's Disease

C. Justin Lee (Institute for Basic Science, Korea)

During the last few years, novel concepts of glia and glymphatic system have dramatically yielded unexpected results that challenge the traditional view of neurological disorders including Alzheimer's disease and other neurodegenerative diseases. They also play a crucial role in maintaining brain homeostasis. This symposium will highlight the latest developments in the reserch of glia and glymphatic system for the CNS in health and disease.

[S-28-4] Novel function of lipid mediators for the microglial fate determination of injured neurons

Hiroshi Kiyama (Dept. of Functional anatomy & Neuroscience, Grad. Sch. Med., Nagoya University, Japan)

During the last few years, novel concepts of glia and glymphatic system have dramatically yielded unexpected results that challenge the traditional view of neurological disorders including Alzheimer's disease and other neurodegenerative diseases. They also play a crucial role in maintaining brain homeostasis. This symposium will highlight the latest developments in the reserch of glia and glymphatic system for the CNS in health and disease.

[S-28-5] Novel homeostatic function of glial cells in health and disease

Makoto Higuchi, Hiroyuki Takuwa (National Institutes for Quantum and Radiological Science and Technology, Japan)

During the last few years, novel concepts of glia and glymphatic system have dramatically yielded unexpected results that challenge the traditional view of neurological disorders including Alzheimer's disease and other neurodegenerative diseases. They also play a crucial role in maintaining brain homeostasis. This symposium will highlight the latest developments in the reserch of glia and glymphatic system for the CNS in health and disease.