[HT-04] Dual nature of REM sleep behavior disorder : parasomnia vs harbinger of synucleinopathies

[HT-04-2] The relationship between REM sleep behavior disorder and hallucinations in patients with DLB

Manabu Ikeda¹, Hideki Kanemoto¹, Kenji Yoshiyama¹, Mamoru Hashimoto², Hiroaki Kazui³ (1.Department of Psychiatry, Osaka University Graduate school of Medicine, Japan, 2.Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University, 3.Department of Neuropsychiatry, Kochi Medical School, Kochi University)

REM sleep behavior disorder (RBD) now attracts much interest from the neurology community, mostly because RBD was incorporated with the revised clinical diagnostic criteria of dementia with Lewy bodies (DLB) as one of the core clinical features in 2017. It has been also well established that RBD often precedes other symptoms and signs of synucleinopathies. Under this circumstance, neurologists should understand what RBD is and to make an early diagnosis of RBD. However, historically RBD was classified as one of the parasomnias with a long history of sleep research, and patients with isolated/idiopathic RBD seek medical help for violent or potentially harmful behaviors during sleep. In this symposium, the speakers from different subspecialties are going to focus this dual nature of RBD. We expect the audience to obtain in-depth knowledge about RBD.

Dr. Ikeda, became the Chairman and Professor, Department of Neuropsychiatry, Kumamoto University in 2007 and is the Chairman & Professor, Department of Psychiatry, Osaka University Graduate School of Medicine since 2016. He graduated from Department of Anthropology, Faculty of Science, University of Tokyo in 1984, and Osaka University Medical School in 1988, and has been engaged with neuropsychology, neuropathology, and old age psychiatry research in Osaka University, Psychiatric Research Institute of Tokyo, Hyogo Institute for Aging Brain and Cognitive Disorders, University of Cambridge, Ehime University School of Medicine, and Kumamoto University. He has published over 150 original papers in English in psychogeriatrics, neuropsychology, and clinical psychiatry. Recent research interest covers epidemiology, symptomatology, neuroradiology, pharmacotherapy and non-pharmacological intervention of dementia, late life depression, and developmental disorders in elderly people.