[HT-04] Dual nature of REM sleep behavior disorder : parasomnia vs harbinger of synucleinopathies

[HT-04-5] 特発性レム睡眠行動異常における臨床試験の準備と方向性

宮本 雅之^1,2,3, 宮本 智之⁴ (1.獨協医科大学 看護学部看護医科学（病態治療）領域, 2.獨協医科大学病院 脳神経内科, 3.獨協医科大学病院 睡眠医療センター, 4.獨協医科大学埼玉医療センター 脳神経内科)

REM sleep behavior disorder (RBD) now attracts much interest from the neurology community, mostly because RBD was incorporated with the revised clinical diagnostic criteria of dementia with Lewy bodies (DLB) as one of the core clinical features in 2017. It has been also well established that RBD often precedes other symptoms and signs of synucleinopathies. Under this circumstance, neurologists should understand what RBD is and to make an early diagnosis of RBD. However, historically RBD was classified as one of the parasomnias with a long history of sleep research, and patients with isolated/idiopathic RBD seek medical help for violent or potentially harmful behaviors during sleep. In this symposium, the speakers from different subspecialties are going to focus this dual nature of RBD. We expect the audience to obtain in-depth knowledge about RBD.

Education:
1988 M.D. Dokkyo Medical University School of Medicine, Japan
1988 - 1990 Residency in Dokkyo Medical University Hospital, Japan
1994　 Ph.D. Dokkyo Medical University Graduate School of Medicine, Japan

Employment:
1994 - present Department of Neurology, Dokkyo Medical University Hospital, Japan
1996 - 2006 Assistant Professor of Neurology, Dokkyo Medical University Hospital, Japan
2006 - 2014 Associate Professor of Neurology, Dokkyo Medical University Hospital, Japan
2009 -present Center of Sleep Medicine, Dokkyo Medical University Hospital, Japan
2014 -present Professor of Dokkyo Medical University School of Nursing, Japan
2015 -present Professor of Dokkyo Medical University Graduate School of Nursing, Japan

Memberships：
Japanese Society of Neurology
The Japanese Society of Internal Medicine
The Japanese Society of Sleep Research
American Academy of Sleep Medicine
World Sleep Society