[HT-10] Motor neuron diseases in the era after translational research

[HT-10-2] Pathogenesis and Therapy of Spinal Muscular Atrophy

Yuh-Jyh Jong^1,2,3 (1.Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Taiwan, 2.Departments of Pediatrics and Laboratory Medicine, Kaohsiung Medical University Chung-Ho Memorial Hospital, Taiwan, 3.College of Biological Science and Technology, National Chiao Tung University, Taiwan)

A recent advance in understanding the pathogenesis of various motor neuron diseases has lead to groundbreaking therapies for motor neuron diseases, including spinobulbar muscular atrophy and spinal muscular atrophy. In ALS, the antisense oligonucleotide therapy and high thruput drug screening using iPS attract huge attention as a promising therapy. This symposium is focussing on therapeutic advances based on the recent innovative translational researches.

Professor Jong Yuh-Jyh is the pioneer researcher of pediatric neuromuscular diseases and the forerunner of multidisciplinary clinic for neuromuscular diseases in Taiwan, and also the founder of Taiwan SMA Families Association. He has been devoted to translational medicine of spinal muscular atrophy, Duchenne muscular dystrophy and other neuromuscular diseases, and the application of biomedical technology in clinical medicine since 1987. Professor Jong is currently served as the President, Kaohsiung Medical University, and Professor, Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, and Visiting Physician, Departments of Pediatrics and Laboratory Medicine, Kaohsiung Medical University Hospital.