[Em-02] Emerging Session 02
Emerging Asian Neurology Session 02 for Dementia and stem cell therapy

[Em-02-1] Roles of the NMDA Receptor GluN3A (NR3A) Subunit in Brain Development and Neurological Diseases

^○Shan Ping Yu^1,2 (1.Emory University School of Medicine, USA, 2.VA Medical Center, USA)

Asian countries are the emerging area of the world not only in economy and culture, but also neurology and neurosceince. This symposium focuses on several neurology topics especially emerging areas of neurology in the emerging Asian countries. Session 1 will focus on Stroke and the Neurosciences with world famous neuroogists and neuroscientists from Asia and USA. Session 2 will focus on Dementia and stem cell therapy with world famous neuroogists and neuroscientists again from Asia and USA.

A.G Candler Endowed Professor
Emory University School of Medicine, Atlanta, USA
Research Biologist
Center for Vision and Neurocognitive Rehabilitation (CVNR)
Veteran’s Affair Medical Center, Atlanta, USA
PUBLICATIONS:
Total papers published: 154 (H factor: 57)
Personal Statement
My research has focused on the mechanisms of neuronal cell death and neuroprotection/regeneration after hypoxia and ischemia. I contributed to the identification of novel ionic and molecular mechanisms in apoptotic and necrotic cell death. We identified specific ion channels, such as Kv2.1 and KCNQ3/4, in mediating apoptotic cell death and neuronal differentiation. We developed the strategy of preconditioning transplanted stem cells and demonstrated the multifaceted pro-survival and pro-regenerative effects of hypoxic preconditioned cells. We developed novel optochemogenetics therapies in stem cell transplantation after ischemic stroke and TBI. I have extended into the investigation of aging related dementia and neurodegenerative disorders. One of our recent progresses is the identification of inflammatory mechanisms that may link early life pain insults to the development of neuropsychological deficits seen in autism-like syndrome. Other research includes direct conversion of glial cells to neurons, drug-induced hypothermia treatments and receptor mechanisms of chronic pain in inflammation and cancer.