[HT-09] Hot Topics 09
Is the concept of embolic stroke of undertermined source (ESUS) dead or alive?

[HT-09-5] Atrial cariopathy as a cause of ESUS

^○Hans C. Diener (Faculty of Medicine and Institute for Med-ical Informatics, Biometry and Epidemiol-ogy at the University of Duisburg-Essen, Germany)

Two clinical trials to compare direct oral anticoagulants (DOACs) and aspirin did not show superiority of DOACs over aspirin in patients with embolic stroke of undertermined source (ESUS). It is argued on the reasons for the negative results that covert atrial fibrilltion may not be a major cause and arteriogenic embolism may be prevalent than ever thought. In this symposium, we analyze the factors affecting the results, reconsider the the currrent concept of EUS, and perspect future direction of antithrombotic therapy.

Prof. Hans-Christoph Diener is affiliated with the Faculty of Medicine and Institute for Medical Informatics, Biometry and Epidemiology at the University of Duisburg-Essen in Essen Germany. He trained as neurologist and worked in Germany, the USA and Australia. He was Chair of Neurology at the University Hospital Essen in Germany from 1989 until 2016 and Senior Professor of Clinical Neurosciences from 2016 to 2019. His research interests are stroke and headache. His h-Index is 110.