[HT-11-3] Biofluid biomarkers for parkinsonian disorders: focusing on blood-based biomarkers
Biomarkers related to the diagnosis and progression of Parkinson's disease are significant for early diagnosis including prodromal stage, prognosis, and development of novel therapies. Even now, there are excellent biomarkers, and although diagnostic criteria for the prodromal stage have been proposed, improvement in diagnostic sensitivity and specificity is inevitable. Based on such a background, recent advances in visualization technology using MRI and nuclear medicine, a more in-depth understanding of the effects of gut microbiota on the pathology, advances in blood biomarker measurement technology such as α-synuclein, and skin pathology are something amazing. In this session, symposists who are specialists in each field will provide the latest information and knowledge. We hope young researchers will envision the direction and potential of future research and encourage their research minds.
EDUCATION:
MD, Shinshu University, 1984
PhD, Shinshu University, 1992
RESEARCH AND PROFESSIONAL ACTIVITIES:
1984.6: Dept. of Neurology, Shinshu University
1993-1995: Visiting Scholar, Dept. of Molecular Biology, Tokyo Institute of Psychiatry
1997-1999: Postdoctoral fellow, Dept. of Pathology (Prof. B. Frangione), NY Univ., USA.
2005-2011: Assistant Professor, Kyoto Prefectural University of Medicine (KPUM)
2011-2013: Associate Professor, KPUM
2014-2020.3: Professor, Dept. of Molecular Pathobiology of Brain Diseases, KPUM
2020.4-: undetermined (as of 2020.1.12)
PROFESSIONAL AND SOCIETY MEMBERSHIPS:
Board Member
2009: Representative, The Japanese Society of Neurology
2010: Councilor, The Japan Society for Dementia Research
2012: Director, The Japanese Society of Normal Pressure Hydrocephalus
MAJOR RESEARCH INTERESTS
1. Protein chemistry and biomarker development in dementing/ neurodegenerative diseases
2. Biochemical analyses of brain-derived extracellular vesicles
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