[S-16] Symposium 16
Autoimmune epilepsy

[S-16-2] Diagnosis of autoimmune epilepsy

^○Mitsuhiro Sakamoto¹, Riki Matsumoto², Akio Ikeda³ (1.Department of Neurology, Rakuwakai Otowa Hospital, Japan, 2.Division of Neurology, Kobe University Graduate School of Medicine, Japan, 3.Department of Epilepsy, Movement Disorders and Physiology, Kyoto University Graduate School of Medicine, Japan)

The epilepsy syndrome of autoimmune etiology, namely, autoimmune epilepsy has attracted attention in recent years. Neural-specific autoantibodies such as anti-NMDA-R and LGI1 antibodies were found, which cause autoimmune epilepsy. Seronegative patients are also existed, and a diagnostic algorithm is required for the diagnosis. Immune therapy should be started in the acute phase as soon as possible in addition to antiepileptic therapy. Especially, new-onset refractory status epilepticus (NORSE) is one of the most challenging status in terms of treatment of acute phase. On the other hand, the presence of smoldering type should be noted with clinical variabilities of autoimmune epilepsy. In this session, pathophysiology, proposal for diagnostic algorithm, management of acute phase, and clinical variabilities of autoimmune epilepsies will be presented by experts in this field.

Education:
2007 Graduated from Kanazawa University School of Medicine (M.D.)
2015 - 2019 PhD course in Department of Neurology, Kyoto University Graduate School of Medicine
Carrier:
2007 - 2009 Resident in Osaka City General Hospital
2009 - 2011 Department of Neurology, Osaka City General Hospital
2011 - 2013 Department of Neurology, Kitano Hospital
2013 - 2015 Department of Neurology, Japanese Red Cross Wakayama Medical Center
2019 - present Medical Director, Department of Neurology, Rakuwakai Otowa Hospital