第61回日本神経学会学術大会

講演情報

シンポジウム

[S-36] シンポジウム36
多系統萎縮症解明へ向けてのnew frontier開拓

2020年9月1日(火) 13:45 〜 15:15 第12会場 (岡山国際交流センター 8F イベントホール)

座長:太田 康之(山形大学医学部内科学第三講座神経学分野),若林 孝一(弘前大学大学院医学研究科脳神経病理学講座)

[S-36-3] How does exogenous alpha-synuclein get access to the endogenous alpha-synuclein proteins?

長谷川 隆文 (東北大学病院 神経・感覚器病態学講座神経内科学分野)

Multisystem atrophy (MSA) is a multi-system neurodegenerative disease of the cerebellum, pyramidal and extrapyramidal tract, and autonomic nervous system, which is characterized by the α-synuclein deposition in oligodendrocytes. There are still many unsolved issues about the pathological mechanism, and there is an urgent need to develop new therapeutic agents. Researches on MSA mainly cover the pathogenesis of α-synuclein, and includes disease-causing factors in DNA polymorphisms and microRNAs, and the dysfunction of neural networks by fMRI. It is important to confirm and discuss about the latest knowledge to develop further researches on MSA. Therefore, in this symposium, the latest research results on MSA in Japan will be presented, aiming discussion between speakers and participants to establish a new research goal on MSA.

photo/S-36-3.jpg
Dr. Hasegawa received his M.D. in 1995 and Ph.D. in 2000 from Tohoku University, Sendai Japan. In 2006, he received Alexander von Humboldt fellowship and joined Dr. Philipp J. Kahle's Lab as a post doc in Hertie-Institute, Tübingen, Germany. In 2008, he went back to Japan and currently he serves as the PI of Parkinson study group in Department of Neurology, Tohoku University School of Medicine. His primary research interest is the functional roles of membrane trafficking in the pathogenesis of Parkinson’s disease (PD) and other neurodegenerative disorders. In addition, Dr. Hasegawa’s group are devoted to establish novel surrogate markers including amyloid PET imaging in synucleinopathy and tauopathy.

抄録パスワード認証
パスワードは抄録集に記載してあります。

パスワード