[S-48] Symposium 48
State-of-the-art basic research for Alzheimer's disease

[S-48-3] Generation of Alzheimer's disease animal models - from mice to non-human primates

^○Hiroki Sasaguri^1,2 (1.Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Japan, 2.Department of Neurology and Neurological Science, Tokyo Medical and Dental University, Japan)

In recent years, many clinical trials for Alzheimer's disease (AD) have ended in disappointment. Now it's time to rethink strategy to defeat AD. In this symposium, researchers at the vanguard of AD basic research will introduce their recent remarkable work, including elucidation of AD pathomechanisms, generation of AD animal models, and establishing new concepts of therapies and biomarkers utilizing cutting-edge technologies. We believe that talk in this session will provide neurologists important insights to gain a better understanding of AD.

1993 - 1999 Tokyo Medical and Dental University (TMDU), Faculty of Medicine
1999 - 2005 TMDU Medical Hospital, Yokosuka Kyosai Hospital, Saitama Rehabilitation Center, Asahi General Hospital, and Kanto Central Hospital
2005 - 2009 Graduate Student, Department of Neurology and Neurological Science, Graduate School, TMDU
2009 - 2012 Saitama Rehabilitation Center
2012 - 2014 Department of Neuroscience, Mayo Clinic, Jacksonville (Prof. Petrucelli)
2014 - 2016 Nitobe Memorial Nakano General Hospital
2016 - 2019 Nov Research fellow, Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science Department of Neurology and Neurological Science, TMDU
2019 Dec - present Deputy Team Leader, Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science Department of Neurology and Neurological Science, TMDU