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Thu. May 20, 2021 8:00 AM - 9:30 AM Room 05 (ICC Kyoto 2F Room B-1)
Chair：Akamatsu Naoki(International University of Health and Welfare School of Medicine, Department of Neurology, International University of Health and Welfare Narita Hospital, Epilepsy Center),Kihara Takeshi(Kobe City Medical Center West Hospital, Department of Neurology)
New evidence is accumulating that late-onset epilepsy of unknown etiology is associated with the risk of developing dementia in elderly people. Interestingly, recent clinicopathological reports using brain specimens resected from patients with refractory temporal lobe epilepsy (rTLE) have shown that deposition of amyloid-b protein and hyperphosphorylation of tau protein, similar to those of Alzheimer’s disease (AD) brains, are found in rTLE brains, indicating a potential pathophysiological link between AD and epilepsy. The goal of the session is to enable the participants to better understand why interdisciplinary research between dementia and epilepsy is significant to create novel and promising therapeutic strategies for dementia.
○Riki Matsumoto (Division of Neurology, Kobe University Graduate School of Medicine, Japan)
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○Akira Kuzuya1, Sakiho Ueda1, Mizuki Matsumoto1, Kazuya Goto2 (1.Department of Neurology, Graduate School of Medicine, Kyoto University, Japan, 2.Department of Regulation of Neurocognitive Disorders, Graduate School of Medicine, Kyoto University)
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○Taira Uehara1,2 (1.Department of Neurology, International University of Health and Welfare Narita Hospital, Japan, 2.Epilepsy Center, International University of Health and Welfare Narita Hospital, Japan)
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○Shuko Takeda (Clinical Gene Therapy, Graduate School of Medicine, Osaka University, Japan)
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