[NFS-03] Neuroscience Frontier Symposium 03 Reassessment APOE4 in Alzheimer's disease

[NFS-03-2] ApoE4 disrupts microcirculation in the white matter

^○Yorito Hattori (Department of Neurology, National Cerebral and Cardiovascular Center, Japan)

Dr. Hattori attended Kansai Medical University and received MD in 2004. He was a neurology resident at Kyoto University Hospital and Kurashiki Chuo Hospital, and then acquired Board Certification in Neurology, Stroke, Dementia, Geriatric Medicine, and Internal Medicine. Dr. Hattori entered Kyoto University Graduate School of Medicine in 2010 to establish novel mouse models of vascular cognitive impairment (VCI), investigate mechanisms of VCI and ischemic stroke, and explore the novel therapeutic agents (e.g., SIRT1 for VCI) (PI: Profs. Ryosuke Takahashi and Masafumi Ihara). He was awarded the Kusano Award in 2016 from the Japan Stroke Society. After receiving PhD, Dr. Hattori worked for Weill Cornell Medicine at New York (PI: Prof. Costantino Iadecola) from 2016 to 2019, and unveiled the importance of ApoE4 role in VCI, and the American Heart Association awarded the VCI Award in 2019. He currently belongs to Department of Neurology, National Cerebral and Cardiovascular Center in Japan.