[Pe-29] English Poster Session 29 ALS (basic research) 02

[Pe-29-6] Optineurin defects cause TDP43-pathology with autophagic vacuolar formation

^○Takashi Kurashige¹, Masato Kuramochi², Ryosuke Ohsawa², Yui Yamashita^3,4, Go Shioi^3,4, Hiroyuki Morino^2,9, Masaki Kamada⁵, Takashi Ayaki⁶, Hidefumi Ito⁷, Yusuke Sotomaru⁸, Hirofumi Maruyama⁹, Hideshi Kawakami² (1.Department of Neurology, National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Japan, 2.Department of Epidemiology, Research Institute for Radiation Biology and Medicine, Hiroshima University, 3.Animal Resource Development Unit, RIKEN Center for Biosystems Dynamics Research, 4.Laboratory for Genetic Engineering, RIKEN Center for Biosystems Dynamics Research, 5.Department of Neurological Intractable Disease Research, Kagawa University Faculty of Medicine, 6.Department of Neurology, Kyoto University Graduate School of Medicine, 7.Department of Neurology, Wakayama Medical University, 8.Natural Science Center for Basic Research and Development, Hiroshima University, 9.9.Department of Clinical Neuroscience and Therapeutics, Graduate School of Biomedical and Health Sciences, Hiroshima University)