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[4O05a1] Alzheimer's Disease and Dementia 2

Sun. Jul 3, 2022 11:00 AM - 12:00 PM Room 5 (Conference Building B2 (Okinawa Convention Center))

Chair: Takashi Saito

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[4O05a1-01] The effect and mechanism of P2Y1 receptor knockout on memory dysfunction in Alzheimer's disease mice

*SHAN LUO¹, Takaki Shirai¹, Ami Tamada¹, Yuichi Saikawa¹, Tatsuhiro Hisatsune¹ (1. The University of Tokyo)

[4O05a1-02] In vivo assessment of progressive astrogliosis in the pathophysiological cascade of rTg4510 tauopathy animal brains

*MASAFUMI SHIMOJO¹, Takeharu Minamihisamatsu¹, Manami Takahashi¹, Hiroyuki Takuwa¹, Yumi Matsushita¹, Rin Yanai¹, Keiichiro Minatohara¹, Maiko Ono¹, Yuhei Takado¹, Ming-Rong Zhang², Naruhiko Sahara¹, Makoto Higuchi¹ (1. Dept. of Func Brain Imaging, QST, Chiba, Japan, 2. Dept. of Ad Nuc Med Sci, QST, Chiba, Japan)

[4O05a1-03] HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimer's disease pathology

*Hikari Tanaka¹, Kanoh Kondo¹, Kyota Fujita¹, Hidenori Homma¹, Kazuhiko Tagawa¹, Xiaocen Jin¹, Meihua Jin¹, Yuki Yoshioka¹, Sumire Takayama¹, Hitoshi Okazawa^1,2 (1. Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, 2. Center for Brain Integration Research)

[4O05a1-04] Identification of the proteins that regulate the Alzheimer's disease-associated splicing of CD33

*Yoshihiro Kino¹, Riho Komuro¹, Yuka Honda¹, Motoaki Yanaizu¹, Jun-ichi Satoh¹ (1. Meiji Pharmaceutical University)

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