[1P] F. Disorders of the Nervous System 2

[1P-146] Insulin deficiency increases Sirt2 level in streptozotocin-treated Alzheimer's disease model mice: Sirt2 increases tau phosphorylation through ERK activation

*Chunyu Zhou¹, Cha-Gyun Jung¹, Mi-Jeong Kim², Atsushi Watanabe³, Mona Abdelhamid¹, Ferdous Taslima¹, Makoto Michikawa¹ (1. Department of Biochemistry, Nagoya City University Graduate School of Medical Sciences, 2. Department of Food & Biotechnology, Korea University, 3. Laboratory of Research Advancement, Research Institute, National Center for Geriatrics and Gerontology)

Keywords:Alzheimer’s disease, Sirt2, tau