[1P] F. Disorders of the Nervous System 2

[1P-157] Beneficial effects of Dimethyl Fumarate on the cognitive impairment and neuroinflammation in Alzheimer's disease mice

*Ting Wang¹, Akira Sobue^1,2, Okiru Komine¹, Seiji Watanabe¹, Takashi Saito³, Takaomi Saido⁴, Koji Yamanaka¹ (1. Nagoya universityDepartment of Neuroscience and Pathobiology, Research InstiDepartment of Neuroscience and Pathobiology, Research Institute of Environmental Medicine, Nagoya University,Japan, 2. Medical Interactive Research and Academia Industry Collaboration Center, Research Institute of Environmental Medicine, Nagoya University,Japan, 3. Department of Neurocognitive Science, Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences Japan, 4. Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science Japan)

Keywords:Alzheimer's disease, neuroinflammation, Nrf2, Astrocyte