[1P] F. Disorders of the Nervous System 2

[1P-171] Identification of antisense oligonucleotides that regulate splicing of tau proteins and their potential therapeutic applications

*Kuniyuki Endo^1,2, Kentaro Sahashi¹, Kaori Kawai¹, Yusuke Fujioka¹, Masahisa Katsuno¹, Gen Sobue³, Shinsuke Ishigaki^1,4 (1. Dept Neurology, Nagoya Univ Grad Sch Med, Nagoya, Japan, 2. Matsukage Hospital, Nagoya, Japan, 3. Aichi Med Univ, Nagakute, Japan, 4. Brain Mind Res Cent, Nagoya University, Nagoya, Japan )

Keywords:4R-Tau associated tauopathies, frontotemporal lobar degeneration (FTLD), Fused in sarcoma (FUS), ENA-antisense oligonucleotides (ENA-ASO)