[1P] F. Disorders of the Nervous System 2

[1P-292] Cellular phenotypes and causal candidate genes in iPSC-derived neurons of a bipolar disorder family

*Gakuya Takamatsu^1,2, Yoko Manome⁴, Kae Koganebuchi^7,6, Dimitar Dimitrov⁸, Kanako Toyama¹, Jun-Seok Lee^1,7, Kumiko Yanagi⁵, Minami Hasegawa⁴, Tomoko Hayakawa^9,1, Tsuyoshi Kondo², Takahashi Tomoyuki⁸, Tadashi Kaname⁵, Hirotaka James Okano⁴, Ryosuke Kimura³, Masayuki Matsushita¹ (1. Dept of Mol Cell Physiol, Grad Sch Med, Univ of the Ryukyus, 2. Dept of Neuropsy, Grad Sch Med, Univ of the Ryukyus, Okinawa, Japan, 3. Dept of Hum Biol Anat, Grad Sch Med, Univ of the Ryukyus, Okinawa, Japan, 4. Div of Regen Med, Jikei Univ Sch of Med, Tokyo, Japan, 5. Dept of Gen Med, Natl Ctr for Chd Hlth Dev, Tokyo, Japan, 6. Dept of Biol Sci, Grad Sch of Sci, Univ of Tokyo, Tokyo, Japan, 7. Adv Med Res Ctr, Fac of Med, Univ of the Ryukyus, Okinawa, Japan, 8. Cel and Mol Syn Func Unit, Okinawa Inst of Sci Tech Grad Univ, Okinawa, Japan, 9. Dept of Phamc, Jichi Med Univ, Tochigi, Japan)

Keywords:bipolar disorder, patient-derived iPSC, mitochondria, psychiatry