[2P] A. Neural Excitability, Synapses, and Glia: Cellular Mechanisms

[2P-061] Delayed Reduction of Excitatory Synapses in CA3 following Systemic Inflammation

*Tatsuya Manabe^1,2, Ildiko Racz^1,2, Stephanie Schwartz^1,2, Francesco Santarelli², Julius V. Emmrich³, Jonas J. Neher^4,5, Michael T. Heneka^1,2,6 (1. Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Center, Bonn, Germany, 2. German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany, 3. Department of Neurology and Experimental Neurology, Charite – Universitatsmedizin Berlin, Berlin, Germany, 4. Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, Tubingen, Germany, 5. German Center for Neurodegenerative Diseases (DZNE), Tubingen, Germany, 6. Department of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, USA)

Keywords:Microglia, Sepsis, Synaptic pruning, Complement